Digital Evidence Base

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Rapid screening of MDR-TB using molecular Line Probe Assay is feasible in Uganda
Bwanga F, Albert H, Mukkada S, Nyesiga B, Ademun JP, Lukyamuzi G, Haile M, Hoffner S, Joloba M, O'Brien R
2010
DOI: 10.1186/1471-2334-10-41

Background: About 500 new smear-positive Multidrug-resistant tuberculosis (MDR-TB) cases are estimated to occur per year in Uganda. In 2008 in Kampala, MDR-TB prevalence was reported as 1.0% and 12.3% in …

Abstract
Third-line antiretroviral therapy in low-income and middle-income countries (ACTG A5288): a prospective strategy study
Grinsztejn B., Hughes M. D., Ritz J., Salata R., Hogg E., Wieclaw L., Gross R., Godfrey C., Cardoso S. W., Bukuru A., Makanga M., Faesen S., Mave V., Wangari Ndege B., Nerette Fontain S., Samaneka W., Secours R., van Schalkwyk M., Mngqibisa R., Mohapi L., Valencia J., Sugandhavesa P., Montalban E., Avihingsanon A., Santos B. R., Kumarasamy N., Kanyama C., Schooley R. T., Mellors J. W., Wallis C. L., Collier A. C., Mugyenyi P.
2019
DOI: 10.1016/s2352-3018(19)30146-8

BACKGROUND: Antiretroviral therapy (ART) management is challenging for individuals in resource-limited settings presenting for third-line treatment because of complex resistance patterns, partly due to reduced access to viral load monitoring. …

Abstract
Clinton Health Access Initiative Annual Report 2015
CHAI
2015

governments to save lives and reduce the burden of disease. This annual report summarized progress that CHAI made in 2015 toward achieving our mission. CHAI was founded with a goal …

Abstract
A review of privacy and usability issues in mobile health systems: Role of external factors
Katusiime Jane, Pinkwart Niels
2019
DOI: 10.1177/1460458217733121

The increased penetration of mobile devices has created opportunities in the health sector and led to emerging of mobile health systems. As much as the mobile health systems have registered …

Abstract
Planning prompts to promote uptake of HIV services among men: A randomised trial in rural Uganda
Kwarisiima D, Chamie G, Thirumurthy H, Kamya M R, Havlir D V, Marson K, Kavanagh N M, Schaffer E M, Ndyabakira A
2020
DOI: 10.1136/bmjgh-2020-003390

Introduction Interventions informed by behaviouraleconomics, such as planning prompts, have the potentialto increase HIV testing at minimal or no cost. Planningprompts have not been previously evaluated for HIVtesting uptake. We …

Abstract
Inverse Correlation Between Seasonal Changes in Home Blood Pressure and Atmospheric Temperature in Treated-Hypertensive Patients
Iwabu Akihiro, Konishi Kumi, Tokutake Hiroe, Yamane Shinichi, Ohnishi Hiromichi, Tominaga Youkou, Kusachi Shozo
2010
DOI: 10.3109/10641963.2010.491886

We examined the relationships between home blood pressure (BP) and atmospheric temperature in 20 treated-hypertensive patients. A significant correlation between morning and evening BP and atmospheric temperature was found. For …

Abstract
Influenza surveillance capacity improvements in Africa during 2011-2017
Lutwama J., Igboh L.S., McMorrow M., Tempia S., Emukule G.O., Talla Nzussouo N., McCarron M., Williams T., Weatherspoon V., Moen A., Fawzi D., Nakoune E., Dauoda C., Kavunga-Membo H., Okeyo M., Heraud J.-M., Mambule I.K., Sow S.O., Tivane A., Lagare A., Adebayo A., Dia N., Mmbaga V., Maman I., Simusika P., Walaza S., Mangtani P., Nguipdop-Djomo P., Cohen C., Azziz-Baumgartner E., Njouom R.
2021
DOI: 10.1111/irv.12818

Background: Influenza surveillance helps time prevention and control interventions especially where complex seasonal patterns exist. We assessed influenza surveillance sustainability in Africa where influenza activity varies and external funds for …

Abstract
Objectively Assessed Physical Activity and Associated Factors Among Adults in Peri-Urban and Rural Eastern Uganda: A Population-based Study
Wamani H, Kirunda BE, Tylleskar T, Fadnes LT, Van den Broeck J
2016
DOI: 10.1123/jpah.2016-0025

Background: Data on physical inactivity, a known risk factor for noncommunicable diseases and its correlates in sub-Saharan Africa are almost absent. We assessed physical activity patterns and associated factors among …

Abstract
Vulnerability and risk to HIV infection in Uganda : multilevel modelling of Uganda AIDS Indicator Survey data
Igulot P
2017

Background. There is controversy on the association between socioeconomic status (SES) and HIV infection. Some evidence claimshigher SES is negatively associated with HIV infection while others report the reverse. Objectives. …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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