Digital Evidence Base

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Transmission of Onchocerca volvulus by Simulium neavei in Mount Elgon focus of eastern Uganda has been interrupted
Lakwo T, Ndyomugyenyi R, Habomugisha P, Byamukama E, Onapa A, Tukesiga E, Katabarwa M, Agunyo S, Oguttu D, Walsh F, Unnasch T R, Ochieng G O, Abwaimo F, Lwamafa D W.K, Richards F O
2014
DOI: 10.4269/ajtmh.13-0501

The study determined that Simulium neavei-transmitted onchocerciasis in Mount Elgon onchocerciasisfocus had been interrupted. Annual mass treatment with ivermectin changed to two times per year along with vectorelimination in 2007. …

Abstract
Community-directed interventions are practical and effective in low-resource communities: Experience of ivermectin treatment for onchocerciasis control in Cameroon and Uganda, 2004-2010
Habomugisha P, Byamukama E, Eyamba A, Katabarwa M N, Nwane P, Arinaitwe A, Musigire J, Tushemereirwe R, Khainza A
2015
DOI: 10.1093/inthealth/ihv038

BackgroundThe community-directed intervention (CDI) approach has improved treatment coverage in onchocerciasis-affected communities. However, there is still a lot to learn. This study assessed its performance and highlighted the lessons learnt …

Abstract
The Imaramagambo Onchocerciasis Focus in Southwestern Uganda: Interruption of Transmission after Disappearance of the Vector Simulium neavei and Its Associated Freshwater Crabs
Lakwo T, Habomugisha P, Byamukama E, Tukahebwa E, Unnasch TR, Tukesiga E, Oguttu D, Khainza A, Katabarwa MN, Katamanywa J, Nahabwe C, Ngabirano M, Richards FO, Garms R
2016
DOI: 10.4269/ajtmh.16-0181

It was not until early 1990s that, when the Imaramagambo focus of southwest Uganda was mapped, mass treatment with a single annual dose of ivermectin for onchocerciaisis control commenced. However, …

Abstract
RECENT SUCCESSFUL CROSS-BORDER ONCHOCERCIASIS ELIMINATION ACTIVITIES - OUR EXPERIENCE
Katabarwa M. N., Lakwo T., Zroug I., Kebede B., Habomugisha P. et al, The Carter Center U. S. A.
2017

AFRICAN DEVELOPMENT Abstract: As the shift from control to elimination of onchocerciasis progresses in Ethiopia, Sudan and Uganda, cross-border transmission has become an increasingly apparent obstacle to success. Without a …

Abstract
After 70 years of fighting an age-old scourge, onchocerciasis in Uganda, the end is in sight
Lakwo T, Habomugisha P, Byamukama E, Tukahebwa E, Unnasch TR, Khainza A, Katabarwa MN, Richards FO, Garms R, Hudson-Davis L, Ngorok J
2018
DOI: 10.1093/inthealth/ihx044

Onchocerciasis causes severe itching, serious skin disease and ocular damage leading to visual impairment or permanent blindness. It is associated with hanging groin, epilepsy, Nakalanga dwarfism and, most recently, nodding …

Abstract
Comparison of reported and survey-based coverage in onchocerciasis programs over a period of 8 years in Cameroon and Uganda
Habomugisha P, Byamukama E, Eyamba A, Katabarwa M N, Richards F O, Nwane P, Khainza A, Griswold E, Bernard L, Weiss P
2019
DOI: 10.4269/ajtmh.18-0680

Mass drug administration (MDA) with ivermectin must reach a high treatment coverage (90% of the eligiblepopulation) if onchocerciasis is to be eliminated. Questions have been raised as to whether reported …

Abstract
Elimination of Simulium neavei-Transmitted Onchocerciasis in Wambabya-Rwamarongo Focus of Western Uganda
Habomugisha P, Byamukama E, Unnasch TR, Oguttu D, Khainza A, Katabarwa MN, Katamanywa J, Nahabwe C, Ngabirano M, Bernard L, Isingooma T, Bwenume F, Akampurira P, Richards F
2020
DOI: 10.4269/ajtmh.20-0195

Wambabya-Rwamarongo onchocerciasis focus is one of the eight foci Uganda verified using the WHO verification guidelines. The approach for elimination was twice yearly treatment with ivermectin for every round, treating …

Abstract
Historical Elimination of Onchocerciasis from Victoria Nile Focus in Central Uganda Verified Using WHO Criteria
Oguttu DW, Habomugisha P, Byamukama E, Unnasch TR, Khainza A, Katabarwa MN, Katamanywa J, Nahabwe C, Ngabirano M, Bernard L, Akampurira P, Richards F
2020
DOI: 10.4269/ajtmh.20-0064

Uganda has verified elimination of seven onchocerciasis foci since 2007 when the nationwide onchocerciasis elimination policy was launched. However, the Victoria Nile focus (which was eliminated in the early 1970s) …

Abstract
Elimination of Simulium neavei-Transmitted Onchocerciasis in Wambabya-Rwamarongo Focus of Western Uganda
KatabarwaMoses N., Habomugisha Peace, Khainza Annet, Oguttu David, Byamukama Edson, Katamanywa James, Isingooma Thomson, Bwenume Fredrick, Nahabwe Christine, Ngabirano Monica, Akampurira Paul, Bernard Lauri, Unnasch Thomas R., Richards Frank
2020

MEDLINE Abstract: Wambabya-Rwamarongo onchocerciasis focus is one of the eight foci Uganda verified using the WHO verification guidelines. The approach for elimination was twice yearly treatment with ivermectin for every …

Abstract
Empiric TB Treatment of Severely Ill Patients With HIV and Presumed Pulmonary TB Improves Survival
Worodria W, Ayakaka I, Cattamanchi A, Davis JL, Walter ND, Kalema N, Huang L, Den Boon S, Katagira W, Vittinghoff E
2016
DOI: 10.1097/QAI.0000000000000970

Rationale: In 2007, World Health Organization (WHO) issued emergency recommendations on empiric treatment of sputum acid-fast bacillus smear-negative patients with possible tuberculosis (TB) in HIV-prevalent areas, and called for operational …

Abstract
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