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The evolving epidemic of breast cancer in sub-Saharan Africa: Results from the African Cancer Registry Network
Joko-Fru WY, Korir A, Parkin DM, Jemal A, Bray F, Jedy-Agba E, Finesse A, Wabinga H, Somdyala N, Chokunonga E, Manraj S, McGale P, Ogunbiyi O, Dzamalala CP, Liu B
2020
DOI: 10.1002/ijc.33014

Breast cancer (BC) is the leading cause of cancer in sub-Saharan Africa (SSA) with rapidly increasing incidence rates reported in Uganda and Zimbabwe. However, the magnitude of these rising trends …

Abstract
Expansion and productive HIV-1 infection of Foxp3 positive CD4 T cells at pleural sites of HIV/TB co-infection
Mayanja-Kizza H., Hirsch C. S., Baseke J., Kafuluma J. L., Nserko M., Toossi Z.
2016

BACKGROUND: CD4 T-cells expressing Foxp3 are expanded systemically during active tuberculosis (TB) regardless of HIV-1 co-infection. Foxp3(+) CD4 T cells are targets of HIV-1 infection. However, expansion of HIV-1 infected …

Abstract
Systematic review of the magnitude and case fatality ratio for severe maternal morbidity in sub-Saharan Africa between 1995 and 2010
Kaye Dan K., Kakaire Othman, Osinde Michael O.
2011

MEDLINE Abstract: BACKGROUND: Analysis of severe maternal morbidity (maternal near misses) provides information on the quality of care. We assessed the prevalence/incidence of maternal near miss, maternal mortality and case …

Abstract
Monitoring and switching of first-line antiretroviral therapy in adult treatment cohorts in sub-Saharan Africa: collaborative analysis
Haas Andreas D., Keiser Olivia, Balestre Eric, Brown Steve, Bissagnene Emmanuel, Chimbetete Cleophas, Dabis François, Davies Mary-Ann, Hoffmann Christopher J., Oyaro Patrick, Parkes-Ratanshi Rosalind, Reynolds Steven J., Sikazwe Izukanji, Wools-Kaloustian Kara, Zannou D. Marcel, Wandeler Gilles, Egger Matthias
2015

MEDLINE Abstract: BACKGROUND:<BR>HIV-1 viral load testing is recommended to monitor antiretroviral therapy (ART) but is not universally available. The aim of our study was to assess monitoring of first-line ART …

Abstract
Ebola hemorrhagic fever outbreaks: Diagnosis for effective epidemic disease management and control
Kang B, Kim H, Macoy D M, Kim M G
2017
DOI: 10.4014/mbl.1701.01001

The first Ebola hemorrhagic fever outbreak occurred in the Democratic Republic of Congo and Sudan in 1976 and then emerged in West Africa in 2014 with a total of 27,741 …

Abstract
First Implant-Induced Changes in Rostral Brainstem Impair Second Implant Outcomes in Sequential Bilateral Cochlear Implant Children With Long Inter-Implant Delay
Kishimoto Ippei, Yamazaki Hiroshi, Naito Yasushi, Moroto Saburo, Yamazaki Tomoko
2019
DOI: 10.1097/MAO.0000000000002130

Hypothesis: Long-term unilateral use of a cochlear implant (CI) induces abnormal maturation of the rostral brainstem innervating the contralateral ear.Background: In sequential bilateral CI children with long inter-implant delay, both …

Abstract
Performance of self-reported adherence to oral pre-exposure prophylaxis (PrEP) among HIV heterosexual serodiscordant couples in rural Uganda
Abaasa A, Ruzagira E, Priddy F, Haberer J, Katende D, Kibengo F M, Bahemuka U M, Barin B, Kampala A
2012

BackgroundAdherence is one of the main determinants of PrEP effi-cacy. Most PrEP studies applied subjective adherencemeasures, which often produce overestimates and proble-matic efficacy data interpretation; creating a need formore objective …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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