Digital Evidence Base

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Insecticide resistance patterns in Uganda and the effect of indoor residual spraying with bendiocarb on kdr L1014S frequencies in Anopheles gambiae s.s.
Abeku TA, Helinski MEH, Kirby MJ, Ssekitooleko J, Bass C, Kyomuhangi I, Okia M, Magumba G, Meek SR
2017
DOI: 10.1186/s12936-017-1799-7

Background: Resistance of malaria vectors to pyrethroid insecticides has been attributed to selection pressure from long-lasting insecticidal nets (LLINs), indoor residual spraying (IRS), and the use of chemicals in agriculture. …

Abstract
Rapid Identification and Susceptibility Testing of Gram-Negative Bacilli from Blood Cultures Using the Vitek 2 System
Bamford C, Goodway J, Hoffmann R
2010

Providing rapid results for blood culture isolates is a critical function of clinical microbiology laboratories. This study evaluated the accuracy and turnaround time for identification and susceptibility testing of Gram-negative …

Abstract
Field evaluation of five rapid diagnostic tests for screening of HIV-1 infections in rural Rakai, Uganda
Gray RH, Serwadda D, Reynolds SJ, Makumbi F, Nakavuma JL, Mills LA, Kagulire SC, Opendi P, Stamper PD, Shott JP
2011
DOI: 10.1258/ijsa.2009.009352

The performance characteristics of HIV rapid diagnostic tests (RDTs) vary by test and by population. We assessed five commercial RDTs in Uganda where all but one RDT (Determine; Abbott Laboratories, …

Abstract
Patterns of human herpesvirus-8 oral shedding among diverse cohorts of human herpesvirus-8 seropositive persons
Celum C, Ignacio RAB, Goldman JD, Magaret AS, Selke S, Huang ML, Gantt S, Johnston C, Phipps WT, Schiffer JT, Zuckerman RA, McClelland RS, Corey L, Wald A, Casper C
2016
DOI: 10.1186/s13027-016-0052-2

Background: Human herpesvirus-8 (HHV-8), the etiologic agent of Kaposi sarcoma (KS), establishes lifelong latent infection with periodic lytic replication ("shedding") at mucosal sites, especially the oropharynx. Patterns of HHV-8 shedding …

Abstract
A Market Landscape and Strategic Approach to Increasing Access to Hearing Aids and Related Services in Low and Middle Income Countries
ATscale
2019

GLOBALLY, AROUND 466 MILLION PEOPLE HAVE DISABLING HEARING LOSS, and this number is expected to double by 2050 due to ageing populations, and new cases of hearing loss caused by …

Abstract
The interface between blood preparation and use in Uganda
Kajja I., Bimenya G., Smit Sibinga C.
2010
DOI: 10.1111/j.1423-0410.2009.01296.x
Abstract
Probiotics; with Special Emphasis on their Role in the Management of Irritable Bowel Syndrome
Blaauw Renee, Stevenson C
2011

Probiotics are live microorganisms; and when administered in adequate amounts; bestow beneficial effects on the host. The therapeutic and preventative application of probiotics in several disorders is receiving increasing attention; …

Abstract
Procalcitonin predicts mortality in HIV-infected Ugandan adults with lower respiratory tract infections
Worodria W, Cattamanchi A, Davis JL, Huang L, Int HIV Assoc Opportunistic Pneumo, Tokman S, Barnett CF, Jarlsberg LG, Taub PR, Den Boon S, Maisel A
2014
DOI: 10.1111/resp.12237

Background and objectiveIn low and middle-income countries where HIV infection is prevalent, identifying patients at high risk of dying from lower respiratory tract infections is challenging and validated prognostic models …

Abstract
Childhood Epilepsy in a Tropical Child Psychiatric Unit: Challenges of Providing Care in a Resource-Constrained Environment
Eseigbe Edwin Ehi Sheikh, Taiwo Lateef Tajudeen Nuhu, Folo
2013

Background: Epilepsy is an important cause of childhood morbidity and its care is fraught with challenges. Itinerantsearch for remedy and manifestation as or with psychiatric disorders could result in presentation …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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