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Ethical tensions in the informed consent process for randomized clinical trials in emergency obstetric and newborn care in low and middle-income countries
Kaye Dan K., Sewankambo Nelson K., Chongwe Gershom
2019
DOI: 10.1186/s12910-019-0363-0

Background: There is unanimous agreement regarding the need to ethically conduct research for improving therapy for patients admitted to hospital with acute conditions, including in emergency obstetric care. We present …

Abstract
The ethical justification for inclusion of neonates in pragmatic randomized clinical trials for emergency newborn care
Kaye D. K.
2019
DOI: 10.1186/s12887-019-1600-x

BACKGROUND: Research guidelines generally recognize vulnerable populations to include neonates with the aim of enhancing protections from harm. In practice, such guidance results in limiting participation in randomized clinical trials …

Abstract
The moral imperative to approve pregnant womenâs participation in randomized clinical trials for pregnancy and newborn complications
Kaye Dan Kabonge
2019
DOI: 10.1186/s13010-019-0081-8

Background: There is longstanding consensus on the need to include pregnant women in research. The goal of clinical research is to find highly regulated, carefully controlled, morally responsible ways to …

Abstract
Lay persons' perception of the requirements for research in emergency obstetric and newborn care
Kaye DK
2021
DOI: 10.1186/s12910-020-00568-1

Background Factors that could potentially act as facilitators and barriers to successful recruitment strategies in perinatal clinical trials are not well documented. The objective was to assess lay persons' understanding …

Abstract
Navigating ethical challenges of conducting randomized clinical trials on COVID-19
Kaye D.K.
2022
DOI: 10.1186/s13010-022-00115-3

BACKGROUND: The contemporary frameworks for clinical research require informed consent for research participation that includes disclosure of material information, comprehension of disclosed information and voluntary consent to research participation. There …

Abstract
Introduction of Newborn Care within Integrated Community Case Management in Uganda
Ssekitooleko J, Magumba G, Waiswa P, Aliganyira P, Kerber K, Gamache N, Mbonye AK, Kallander K, Kayemba CN, Sengendo HN, Guenther T, Strachan C, Ocan C, Counihan H, Marsh DR
2012
DOI: 10.4269/ajtmh.2012.12-0133

Uganda's Ministry of Health, together with partners, has introduced integrated community case management (iCCM) for children under 5 years. We assessed how the iCCM program addresses newborn care in three …

Abstract
Impact of mode of delivery on pregnancy outcomes in women with premature rupture of membranes after 28 weeks of gestation in a low-resource setting: A prospective cohort study
Byamugisha Josaphat, Lester Felicia, Kayiga Herbert, Amuge Pauline Mary, Autry Amy Meg
2018

MEDLINE Abstract: BACKGROUND:<BR>Despite the high prevalence of premature rupture of membranes (PROM) in low-resource settings, the preferred mode of delivery remains unclear. We compared the perinatal mortality in a prospective …

Abstract
Impact of genital Chlamydia trachomatis infection on reproductive outcomes among infertile women undergoing tubal flushing: a retrospective cohort at a fertility centre in Uganda
Kayiira A., Zaake D., Lwetabe M. W., Sekweyama P.
2019
DOI: 10.1186/s40738-019-0069-5

BACKGROUND: The impact of current C. trachomatis on clinical pregnancy and live birth rates among women undergoing tubal flushing is largely unknown. This study aimed to investigate whether current female …

Abstract
HIV/AIDS related knowledge and perceived risk associated with condom use among adolescents in Uganda
Kayiki Simon P, Forste Renata
2011

While considerable attention has been paid to sexual behaviors among HIV high-risk populations in Africa, few studies have looked at the adolescent population. Using data from the 2004 National Survey …

Abstract
Hypertension awareness, treatment and control in Africa: a systematic review
Kayima James, Wanyenze Rhoda K., Katamba Achilles, Leontsini Elli, Nuwaha Fred
2013

MEDLINE Abstract: BACKGROUND:<BR>Inadequate diagnosis and suboptimal control of hypertension is a major driver of cardiovascular morbidity and mortality in Africa. Understanding the levels of awareness, treatment and control of hypertension …

Abstract
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