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Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
Paediatric admissions and outcome in a general intensive care unit
Embu Henry Y, Yiltok Simon J, Isamade Erdoo S, Nuhu Samuel I, Oyeniran Olushola O, Uba Francis A
2011

Background: It is believed that intensive care greatly improves the prognosis for critically ill children and that critically ill children admitted to a dedicated Paediatric Intensive Care Unit (PICU) do …

Abstract
Readiness of Ugandan health services for the management ofoutpatients with chronic diseases
Biraro S, Mutungi G, Smeeth L, Baisley K, Grosskurth H, Munderi P, Katende D, Ikoona E, Peck R, Hayes R
2015
DOI: 10.1111/tmi.12560

ObjectiveTraditionally, health systems in sub-Saharan Africa have focused on acute conditions. Few data exist on the readiness of African health facilities (HFs) to address the growing burden of chronic diseases …

Abstract
Reverse zoonotic tuberculosis transmission from an emerging Uganda I strain between pastoralists and cattle in South-Eastern Nigeria
Adesokan HK, Akinseye VO, Streicher EM, Van Helden P, Warren RM, Cadmus SI
2019
DOI: 10.1186/s12917-019-2185-1

Background: Tuberculosis remains a major public health challenge globally with increasing risks for inter-transmission between pastoralists and cattle in Nigeria. This study was aimed at using molecular tools to establish …

Abstract
Fragile, threatened, and still urgently needed: Family planning programs in sub-Saharan Africa
Jacobstein Roy, Bakamjian Lynn, Pile John M., Wickstrom Jane
2009
DOI: 10.1111/j.1728-4465.2009.00197.x

Many family planning (FP) programs in sub-Saharan Africa are fragile; recent performance has fallen off and future performance is challenged. Yet robust and well functioning FP programs are still urgently …

Abstract
Civilian Counselorsâ Perspectives on Military Competence and Treatment for Active-Duty Service Members Diagnosed with Post Traumatic Stress
Grimes Leeshe N.
2021

The study investigated how licensed nonmilitary mental health professionals describe their military and cultural competence in adapting treatment approaches for active-duty service members diagnosed with posttraumatic stress disorder (PTSD) in …

Abstract
Polygyny and intimate partner violence in sub-Saharan Africa: Evidence from 16 cross-sectional demographic and health surveys
Ahinkorah BO
2021
DOI: 10.1016/j.ssmph.2021.100729

In sub-Saharan Africa, where intimate partner violence has been found to be predominant, several scholars have made efforts to understand its predictors. Socio-culturally, polygyny has been considered as a key …

Abstract
Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2
McCarthy K, IMPAACT 2010 Vested Study Team, Lockman S, Ziemba L, Jean-Philippe P, Johnston B, Krotje C, Stranix-Chibanda L, Sax PE, Moyo S, Stringer JSA, Masheto G, Korutaro V, Cassim H, Joao E, Hanley S, Purdue L, Holmes LB, Momper JD, Shapiro RL, Thoofer NK, Frenkel LM, Amico KR, Chinula L, Currier J, Rooney JF, Hoffman RM, Brummel SS, Fairlie L, Coletti A, Chakhtoura N, Mmbaga BT
2021

Background Antiretroviral therapy (ART) during pregnancy is important for both maternal health and prevention of perinatal HIV-1 transmission; however adequate data on the safety and efficacy of different ART regimens …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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