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Analysis of the gut-specific microbiome from field-captured tsetse flies, and its potential relevance to host trypanosome vector competence
Echodu R, Aksoy S, Griffith BC, Weiss BL, Aksoy E, Mireji PO, Auma JE, Wamwiri FN, Murilla G
2018
DOI: 10.1186/s12866-018-1284-7

Background: The tsetse fly (Glossina sp.) midgut is colonized by maternally transmitted and environmentally acquired bacteria. Additionally, the midgut serves as a niche in which pathogenic African trypanosomes reside within …

Abstract
Predicting HIV Incidence in the SEARCH Trial: A Mathematical Modeling Study
Clark TD, Kamya MR, Havlir DV, Bershteyn A, Balzer LB, Charlebois ED, Kwarisiima D, Petersen ML, Jewell BL
2021
DOI: 10.1097/QAI.0000000000002684

Background: The SEARCH study provided community-based HIV and multidisease testing and antiretroviral therapy (ART) to 32 communities in East Africa and reported no statistically significant difference in 3-year HIV incidence. …

Abstract
Social autopsy: INDEPTH Network experiences of utility, process, practices, and challenges in investigating causes and contributors to mortality
Kadobera D, Waiswa P, Kallander K, Yevoo L, Amu A, Williams TN, Nielsen RT, Mutebi A, Akpakli J, Narh C, Gyapong M
2011
DOI: 10.1186/1478-7954-9-44

Background: Effective implementation of child survival interventions depends on improved understanding of cultural, social, and health system factors affecting utilization of health care. Never the less, no standardized instrument exists …

Abstract
Immunovirological response to combined antiretroviral therapy and drug resistance patterns in children: 1- and 2-year outcomes in rural Uganda
Ahoua L, Guenther G, Rouzioux C, Pinoges L, Anguzu P, Taburet AM, Balkan S, Olson DM, Olaro C, Pujades-Rodriguez M
2011
DOI: 10.1186/1471-2431-11-67

Background: Children living with HIV continue to be in urgent need of combined antiretroviral therapy (ART). Strategies to scale up and improve pediatric HIV care in resource-poor regions, especially in …

Abstract
"Now that you are circumcised, you cannot have first sex with your wife": post circumcision sexual behaviours and beliefs among men in Wakiso district, Uganda
Makumbi FE, Kibira SPS, Sandoy IF, Daniel M, Atuyambe LM
2017
DOI: 10.7448/IAS.20.1.21498

Introduction: Safe male circumcision is an important biomedical intervention in the comprehensive HIV prevention programmes implemented in 14 sub-Saharan African countries with high HIV prevalence. To sustain its partial protective …

Abstract
Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria
Wang F., Kain K.C., Higgins S.J., Xing K., Kim H., Kain D.C., Dhabangi A., Musoke C., Cserti-Gazdewich C.M., Tracey K.J., Liles W.C.
2013
DOI: 10.1186/1475-2875-12-105
Abstract
Approaches to accelerating the study of new antiretrovirals in pregnancy
Abrams E.J., Calmy A., Fairlie L., Mahaka I.C., Chimula L., Flynn P.M., Kinuthia J., Myer L., Khoo S.H., Musoke P., Zwerski S., Zech J.M., Lockman S., Siberry G.K.
2022
DOI: 10.1002/jia2.25916

Introduction: Women who are pregnant or who could become pregnant experience delayed access to or underinformed use of important new antiretroviral (ARV) drugs because of traditional drug development processes that …

Abstract
Promoting pediatric oncology nursing excellence in sub-Saharan Africa using project ECHO
Higgins J., Hockenberry M., Bank R., Nedege A., Mulemba T., Nakabiri J., Raletshegwana M., Semetsa P.
2021
DOI: 10.1016/j.ijans.2021.100363

Purpose: The designation of the year 2020 as the International Year of the Nurse provides time for reflection on the importance of nursing in meeting the needs of the under-served …

Abstract
Global pattern and trends of colorectal cancer survival: a systematic review of population-based registration data
Li Z., Jiang Y., Yuan H., Ji X., Shen Q., Tuo J., Bi J., Li H., Xiang Y.
2022
DOI: 10.20892/j.issn.2095-3941.2020.0634
Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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