Digital Evidence Base

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Escherichia coli, a pathogen under fire from the news
Grp Pathologie Infect Pediat, Cohen R, Raymond J, Gendrel D, Bingen E
2012

Escherichia coli is both a gastrointestinal tract commensal and a major pathogen. In recent years, E. coli is under lire from the news due to a better understanding of pathogenic …

Abstract
Disparities in Injury Mortality Between Uganda and the United States: Comparative Analysis of a Neglected Disease
Ozgediz D, Lipnick MS, Jayaraman S, Miyamoto J, Caldwell N, Mijumbi C, Mabweijano J, Hsia R, Dicker R
2011
DOI: 10.1007/s00268-010-0871-z

The burden of global injury-related deaths predominantly affects developing countries, which have little infrastructure to evaluate these disparities. We describe injury-related mortality patterns in Kampala, Uganda and compare them with …

Abstract
A Comparison of Post-Incisional Subcutaneous; Intramuscular; and Subcutaneous plus Intramuscular Infiltrations of Lidocaine in Post-Caesarean Pain Control
Fouladi R. F, Navali N, Nikpour M. A
2012

Background. How best to relieve pain after caesarean section (CS) is still debated by many obstetricians. Pre- and post-incisional infiltrations with local anaesthetics have been widely tested and compared. However; …

Abstract
Detecting adenosine triphosphatase 6 (pfATP6) point mutations that may be associated with Plasmodium falciparum resistance to artemisinin: prevalence at baseline, before policy change in Uganda
Kaddumukasa Mark, Kironde Fred, Kamugisha Erasmus, Sendagire Hakim, Enweji Nizar, Gheysari Fatemeh, Swedberg Göte
2011

MEDLINE Abstract: The artemisinin based combination therapy (ACT) of artemether and lumefantrine (Co-artem) has recently replaced chloroquine and fansidar as the first line treatment policy drug in Uganda. It is …

Abstract
Special issue: newborn health in Uganda
Waiswa P., Peterson S., Kerber K.
2015
DOI: 10.3402/gha.v8.27574
Abstract
Piperaquine Exposure Is Altered by Pregnancy, HIV, and Nutritional Status in Ugandan Women
Muhindo M, Hughes E, Mwebaza N, Kajubi R, Aweeka F, Imperial M, Wallender E, Jagannathan P, Mwima M W, Clark T D, Opira B, Nakalembe M, Savic R M, Rosenthal P J, Zhang N, Natureeba P, Dorsey G, Kakuru A, Havlir D, Kamya M, Huang L
2020
DOI: 10.1128/AAC.01013-20

Dihydroartemisinin-piperaquine (DHA-PQ) provides highly effective therapy and chemoprevention for malaria in pregnant African women. PQ concentrations of >10.3âng/ml have been associated with reduced maternal parasitemia, placental malaria, and improved birth …

Abstract
Evaluating the effect of the Helping Mothers Survive Bleeding after Birth (HMS BAB) training in Tanzania and Uganda: study protocol for a randomised controlled trial
Hanson C, Atuhairwe S, Marrone G, Kaharuza F, Alwy F, Pembe AB, HMS BAB study team, Leshabari S, Morris J
2017
DOI: 10.1186/s13063-017-2056-7

Background: Postpartum haemorrhage complicates approximately 10% of all deliveries and contributes to at least a quarter of all maternal deaths worldwide. The competency-based Helping Mothers Survive Bleeding after Birth (HMS …

Abstract
Comforting strategies and perceived barriers to pediatric pain management during IV line insertion procedure in Uganda's national referral hospital: A descriptive study
Katende G, Mugabi B
2015
DOI: 10.1186/s12887-015-0438-0

Background: Venipuncture and intravenous (IV) cannula insertions are the two common sources of pain in hospitalized children and health care today. The WHO asserts that, pain relief is a basic …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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