Digital Evidence Base

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Comment on: The seroprevalence of Helicobacter pylori and its relationship to malaria in Ugandan children
Hestvik E., Tylleskar T.
2012
DOI: 10.1016/j.trstmh.2012.02.002
Abstract
The Receptor SIGIRR Suppresses Th17 Cell Proliferation via Inhibition of the Interleukin-1 Receptor Pathway and mTOR Kinase Activation
Gulen Muhammet F, Kang Zizhen, Bulek Katarzyna, Youzhong Wan, Kim Tae Whan, Chen Yi, Altuntas Cengiz Z, Sass Bak-Jensen Kristian, McGeachy Mandy J, Do Jeong-Su, Xiao Hui, Delgoffe Greg M, Min Booki, Powell Jonathan D, Tuohy Vincent K, Cua Daniel J, Li Xiaoxia
2010
DOI: 10.1016/j.immuni.2009.12.003

Interleukin-1 (IL-1)-mediated signaling in TÂ cells is essential for T helper 17 (Th17) cell differentiation. We showed here that SIGIRR, a negative regulator of IL-1 receptor and Toll-like receptor signaling, …

Abstract
Indicators for routine monitoring of effective mental healthcare coverage in low- and middle-income settings: a Delphi study
Hanlon C, Kigozi F, Petersen I, Shidhaye R, Lund C, Thornicroft G, Semrau M, Alem A, Abdulmalik J, Gureje O, Mugisha J, Jordans MJD, Chisholm D, Upadhaya N, Ahuja S
2016
DOI: 10.1093/heapol/czw040

High-quality information to measure the need for, and the uptake, cost, quality and impact of care is essential in the pursuit of scaling up mental health care in low- and …

Abstract
Coping and Post-traumatic Growth Among COVID-19 Patients: A Qualitative Study
Gökalp Zeynep ÅimÅir, Koç Hayri, Kozan Hatice Ä°rem Ãzteke
2022
DOI: 10.1007/s10804-022-09398-4

Pandemic diseases have caused dramatic changes in peopleâs lives throughout history. Today, the COVID-19 virus spreads rapidly and affects human beings around the globe. This study aimed to discover the …

Abstract
HIV-Related Stigma Among Youth Living With HIV in Western Uganda
Vindevogel S, Kimera E, Rubaihayo J, Reynaert D, De Maeyer J, Engelen AM, Bilsen J, Kintu MJ
2021
DOI: 10.1177/10497323211012347

We present an explanatory theory for HIV-related stigma from the perspectives of youth living with HIV/AIDS (YLWHA) in Western Uganda, on which the fight against this relentless stigma in this …

Abstract
HIV MARKET REPORT The state of HIV treatment, testing, and prevention in low- and middle-income countries
CHAI
2019

The first edition of CHAI s HIV Market Report (then called the ARV Market Report) came out in 2010. When it was published, under 8 million patients were on antiretroviral …

Abstract
Occurence of Culturable Vibrio cholerae from Lake Victoria, and Rift Valley Lakes Albert and George, Uganda
Kaddumukasa M, Nsubuga D, Muyodi F J
2012
DOI: 10.1111/lre.12009

Vibrio cholerae, a bacterium that causes cholera, poses a human health risk when consumed via untreated or contaminated water. Monthly investigations into the presence of V. cholerae from Lakes Albert, …

Abstract
Declining HIV incidence in sub-Saharan Africa: a systematic review and meta-analysis of empiric data
Grabowski MK, Tobian AAR, Joshi K, Lessler J, Olawore O, Loevinsohn G, Bushey S
2021
DOI: 10.1002/jia2.25818

Introduction UNAIDS models suggest HIV incidence is declining in sub-Saharan Africa. The objective of this study was to assess whether modelled trends are supported by empirical evidence. Methods We conducted …

Abstract
Awareness of, responsiveness to and practice of patients' rights at Uganda's national referral hospital
Ekirapa-Kiracho E, Kagoya H R, Kibuule D, Mitonga-Kabwebwe H, Ssempebwa J C
2013
DOI: 10.4102/phcfm.v5i1.491

Background: The realisation of patientsâ rights in resource-constrained and patient-burdened publichealth care settings in Uganda remains an obstacle towards quality health care delivery, health care-seeking behaviour and health outcomes. Although …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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