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Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein
Holtsberg FW, Shulenin S, Vu H, Howell KA, Douglas R, Froude JW, Herbert AS, Wirchnianski AS, Lear-Rooney CM, Dye JM, Glass PJ, Warfield KL, Aman MJ, Keck ZY, Enterlein SG, Araghi N, Biggins J, Lau P, Wang Y, Foung SKH
2016
DOI: 10.1128/JVI.02172-15

Filoviruses cause highly lethal viral hemorrhagic fever in humans and nonhuman primates. Current immunotherapeutic options for filoviruses are mostly specific to Ebola virus (EBOV), although other members of Filoviridae such …

Abstract
Analysis and visualisation of research trends in community maternal care: A general review
Keerthana S., Maunika
2020

Maternal care is a very important pillar of a healthy society. Community health measures play a significant role in improving the quality of maternal care and thereby reducing maternal mortality. …

Abstract
T cell responses to SARS-CoV-2 spike cross-recognize Omicron
Mendes A., Strydom A., Venter M., Giandhari J., Naidoo Y., Pillay S., Tegally H., Grifoni A., Weiskopf D., Sette A., Wilkinson R.J., Suzuki A., Gray G., Stek C., Ueckermann V., Rossouw T., Boswell M.T., Bihman J., Moore P.L., Sigal A., Ntusi N.A.B., Burgers W.A., Riou C., van den Berg G., Aremu O., Keeton R., Tincho M.B., Ngomti A., Baguma R., Benede N., de Oliveira T., Khan K., Cele S., Bernstein M., Karim F., Madzorera S.V., Moyo-Gwete T., Mennen M., Adriaanse M., Mutithu D., Skelem S., du Bruyn E., Van Der Mescht M.A., de Beer Z., de Villiers T.R., Bodenstein A., Bekker L.-G.
2022
DOI: 10.1038/s41586-022-04460-3

The SARS-CoV-2 Omicron variant (B.1.1.529) has multiple spike protein mutations1,2 that contribute to viral escape from antibody neutralization3â6 and reduce vaccine protection from infection7,8. The extent to which other components …

Abstract
An immunohistochemical marker panel including claudin-18, maspin, and p53 improves diagnostic accuracy of bile duct neoplasms in surgical and presurgical biopsy specimens
Keira Yoshiko, Takasawa Akira, Murata Masaki, Nojima Masanori, Takasawa Kumi, Ogino Jiro, Higashiura Yukimura, Sasaki Ayaka, Kimura Yasutoshi, Mizuguchi Toru, Tanaka Satoshi, Hirata Koichi, Sawada Norimasa, Hasegawa Tadashi
2015
DOI: 10.1007/s00428-014-1705-4

Biliary tract cancers have an extremely poor outcome, and specific diagnostic markers and effective treatments are needed urgently. In this study, we assessed the capacity of panel of immunohistochemical markers …

Abstract
Models of evaluating the clinical significance of depression treatment in developing countries: The case of group interpersonal psychotherapy in rural southwestern Uganda
Keith Jessica Anne
2010

Depression in the developing world is highly prevalent and associated with a range of negative outcomes. Evidence-based treatment for depression in the developing world is rare and, when implemented, tends …

Abstract
Post-traumatic stress disorder among persons with HIV who engage in heavy alcohol consumption in southwestern Uganda
Kamya M, Adong J, Fatch R, Emenyonu NI, Muyindike WR, Hahn JA, Kekibiina A, Chamie G, Marson K, Beesiga B, Lodi S, McDonell MG
2021
DOI: 10.1186/s12888-021-03464-z

Background We aimed to describe the prevalence of PTSD symptoms and its associated factors in persons living with HIV (PLWH) in Uganda who engage in heavy alcohol use. Methods We …

Abstract
Comparing banana leaf dressing and vaseline gauze dressing for split-thickness skin graft donor sites in a ugandan hospital
Kekisa N L, Galiwango G, Hodges A
2021
DOI: 10.4314/AAS.V18I1.2

Introduction: This study compared the effectiveness ofbanana leaf dressing (BLD) with the commonly usedVaseline gauze dressing (VGD) on split-thickness skingraft (SSG) donor sites. VGD is not completely nonadherent and is …

Abstract
Prospective Long-term Outcomes of a Cohort of Ugandan Children with Laboratory Monitoring During Antiretroviral Therapy
Kekitiinwa A, Korutaro V, Kasirye P, Asiimwe A R, Kitaka S, Maganda A, Madalon M, Graziano F M
2012
DOI: 10.1097/INF.0b013e31825cb9d6

Background: Treatment of HIV-1 infected Ugandan children with antiretroviral therapy (ART) is increasing, but few prospective long-term studies evaluating the treatment process have been reported. In this study, we sought …

Abstract
Acceptability of lopinavir/r pellets (minitabs), tablets and syrups in HIV-infected children
Musiime V, Kekitiinwa A, Mirembe G, Gibb DM, Thomason MJ, Lallemant M, Nakalanzi S, Baptiste D, Walker AS, Judd A
2016
DOI: 10.3851/IMP3054

Background: Lopinavir/ritonavir 'pellets' were recently tentatively approved for licensing. We describe their acceptability for infants and children up to 48 weeks.Methods: CHAPAS-2 was a randomized, two-period crossover trial comparing syrup …

Abstract
Virologic Response to First-line Efavirenz-or Nevirapine-based Antiretroviral Therapy in HIV-infected African Children
Gibb D.M., Spyer M., Musiime V., Bakeera-Kitaka S., Mhute T., Kekitiinwa A., Walker A.S., Szubert A.J., Katuramu R., Senfuma O.
2017
DOI: 10.1097/INF.0000000000001505
Abstract
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