Digital Evidence Base

Trusted Knowledge for Informed Decisions

Filters
SDGs
Priority Areas
Research Outcomes
Document Type
Year
4019 results found
Show:
Sensitivity, specificity of biochemical markers for early prediction of endotheliadysfunction in atherosclerotic obese subjects
Abulnaja K.O., Kannan K., Al-Manzlawi A.M.K., Kumosani T.A., Qari M., Moselhy S.S.
2022
DOI: 10.4314/ahs.v22i2.32

Background: The obesity increased incidence of diabetes, hypertension and atherosclerosis and rate of morbidity and mortality. The main cause of atherosclerosis is endothelial dysfunction and formation of foam cells and …

Abstract
Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis
Corstjens P.L.A.M., Tjon Kon Fat E.M., de Dood C.J., Rosenkrands I., Aagaard C., Kaufmann S.H.E., Esterhuyse M.M., Cliff J.M., Dockrell H.M., Franken K., Howe R., Mayanja-Kizza H., Jacobs R., Awoniyi D.O., Baumann R., Stanley K., McAnda S., Kaempfer S., Malherbe S.T., Singh M., Walzl G., Chegou N.N., Kriel M., van der Spuy G., Loxton A.G., Kriel B., Sutherland J.S., Owolabi O., Sillah A., Mendy J., Gindeh A., Donkor S., Togun T., Simukonda F., Amberbir A., Chilongo F., Houben R., Kassa D., Gebrezgeabher A., Mesfin G., Belay Y., Crampin A.C., Gebremichael G., Alemayehu Y., van der Vyver M., Amutenya F.N., Nelongo J.N., Monye L., Sheehama J.A., Iipinge S., Namuganga A.R., Muzanye G., Nsereko M., Peters P., Mihret A., Bekele Y., Tessema B., Yamuah L., Ottenhoff T.H.M., Geluk A., Ota M., van der Ploeg-van Schip J.J.
2022
DOI: 10.1016/j.tube.2022.102169

Background: Antibodies against mycobacterial proteins are highly specific, but lack sensitivity, whereas cytokines have been shown to be sensitive but not very specific in the diagnosis of tuberculosis (TB). We …

Abstract
HIV-Associated Gut Microbiome Differences and Immune Activation Are Dependent on Host Context
Gootenberg David B.
2019

Even with antiretroviral therapy, individuals infected with Human Immunodeficiency Virus (HIV) experience greater mortality than uninfected individuals. This mortality is due in large part to inflammation-related non-communicable diseases, such as …

Abstract
Routine Healthcare Facility- and Antenatal Care-based Malaria Surveillance: Challenges and Opportunities
Gutman J.R., Thwing J., Mwesigwa J., McElroy P., Robertson M.
2022
DOI: 10.4269/ajtmh.22-0182

Most monitoring and evaluation tools for measuring malaria burden, intervention coverage, and impact of interventions use periodic nationally representative cross-sectional household surveys. These provide advantages in terms of selecting a …

Abstract
Implementation of a standardised and quality-assured enhanced gonococcal antimicrobial surveillance programme in accordance with WHO protocols in Kampala, Uganda
Lamorde M, Walwema R, Kiggundu R, Kyambadde P, Manabe YC, Kakooza F, Musinguzi P, Workneh M, Mande E, Lubega C, Nakasi JM, Hamill MM, Bagaya BS, Unemo M
2021
DOI: 10.1136/sextrans-2020-054581

ObjectivesThe emergence of multidrug-resistant Neisseria gonorrhoeae (NG) is a major global health threat necessitating response and control measures. NG antimicrobial resistance (AMR) surveillance data from sub-Saharan countries is exceedingly limited. …

Abstract
BRIDEWEALTH PAYMENT AND ACTUAL CONTRACEPTIVE BEHAVIOR IN UGANDA
Dodoo Naa Dodua, Dodoo F. Nii-Amoo
2017
Abstract
KeyLoop: Mechanical Retraction of the Abdominal Wall for Gasless Laparoscopy
Gupta A., Brown E., Davis J.T., Sekabira J., Ramanujam N., Mueller J., Fitzgerald T.N.
2022
DOI: 10.1177/15533506211031084

Background. Despite favorable outcomes of laparoscopic surgery in high-income countries, its implementation in low- and middle-income countries (LMICs) is challenging given a shortage of consumable supplies, high cost, and risk …

Abstract
Motor Neuron Disease: The Impact of Decreased Speech Intelligibility on Marital Communication
Bornman Juan, Joubert Karin
2012

Background: The onset of motor neuron disease (MND); a neurodegenerative disease; results in physical and communication disabilities that impinge on an individual's ability to remain functionally independent. Multiple aspects of …

Abstract
Developing and Validating an Effective Pediatric and Adolescent HIV Testing Eligibility Screening Tool for High-Volume Entry Points in Uganda
Kekitiinwa A, Kazooba P, Katureebe C, Ashburn K, Machekano R, Gill MM, Gross J, Kiyonga A, Taasi G, Adler M, Nazziwa E, Rivadeneira ED, Magongo E, Matovu JB, Nantume S, Bitarakwate E
2021
DOI: 10.1097/QAI.0000000000002775

Introduction: Because of low pediatric HIV prevalence, more tests are needed to find 1 HIV-positive child compared with adults. In Uganda, the number needed to test (NNT) to find 1 …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
AI Research Assistant
AI-powered research assistance. Uses the Digital Evidence Base as the Knowledge source.