Digital Evidence Base

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Reply to comment on: The seroprevalence of Helicobacter pylori and its relationship to malaria in Ugandan children
Gupta V., Perez-Perez G.I., Dorsey G., Rosenthal P.J., Blaser M.J.
2012
DOI: 10.1016/j.trstmh.2012.02.003
Abstract
Congenital Heart Disease in East Africa
Lubega S, Jivanji SGM, Reel B, Qureshi SA
2019
DOI: 10.3389/fped.2019.00250

Congenital Heart Disease (CHD) is an enormous problem in Low Middle Income Countries and particularly in sub-Saharan Africa. There is an estimated 500,000 children born in Africa with CHD each …

Abstract
Use of community engagement interventions to improve child immunisation in lowâ and middleâincome countries: A systematic review and metaâanalysis
Jain Monica, Shisler Shannon, Lane Charlotte, Bagai Avantika, Brown Elizabeth, Engelbert Mark, Vardy Yoav, Eyers John, Daniela Anda Leon, Parsekar Shradha S
2022
DOI: 10.1002/cl2.1253

Immunisation is one of the most costâeffective interventions to prevent and control lifeâthreatening infectious diseases. Nonetheless, rates of routine vaccination of children in lowâ and middleâincome countries (LMICs) are strikingly …

Abstract
Silencing distressed children in the context of war in northern Uganda: An analysis of its dynamics and its health consequences
Akello G, Reis R, Richters A
2010
DOI: 10.1016/j.socscimed.2010.03.030

Children in northern Uganda who are the focus of this article were born and raised in the context of war. The research presented here is based on a one-year ethnographic …

Abstract
Increasing options for post abortion care, medical abortion and contraception in women with unwanted pregnancies
Association of Obstetricians and Gynecologists of Uganda (AOGU

Background: In Uganda, 56% of all pregnancies are unintended, and the maternal mortality ratio remains unacceptably high at 336 deaths/100,000 live births [1]. Unsafe abortions, mainly from unwanted pregnancies, contribute …

Abstract
Monocyte activation in persons living with HIV and tuberculosis coinfection
Longenecker CT, Huaman MA, Nalukwago S, Nazzinda R, Fichtenbaum CJ, Juchnowski SM, Zidar DA, Kityo CM
2021
DOI: 10.1097/QAD.0000000000002766

Objectives: To characterize monocyte subsets and activation in persons living with HIV (PLWH) with tuberculosis coinfection. Design: Cross-sectional study within a cohort of PLWH and HIV-uninfected participants at the Joint …

Abstract
Brief Report: Prevalence of Latent Rheumatic Heart Disease among HIV-Infected Children in Kampala, Uganda
Musiime V, Kityo C, Mirembe G, Lubega S, Lwabi P, Gleason B, Namuyonga J, Okello E, Lubega I, Salata R A, Longenecker C T
2016
DOI: 10.1097/QAI.0000000000000827

Rheumatic heart disease (RHD) remains highly prevalent in resource-constrained settings around the world, including countries with high rates of HIV/AIDS. Although both are immune-mediated diseases, it is unknown whether HIV …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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