Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative medicine, is a promising new intervention that aims to repair or replace tissue or organ function lost due to damage or congenital defects.Rapid Response Questions: What is the role of stem cell therapy in the management of non-communicable diseases? How does it work, and what are its implications for the health system?Findings: Stem cell therapy has the potential to improve clinical outcomes for chronic diseases, with studies showing consistent improvement in myocardial function and safety through autologous bone marrow stem cell transplantation in myocardial infarction. It may also improve social and economic aspects for households affected by chronic degenerative diseases. However, translating stem cell research into policy and practice faces barriers, including ethical, financial, human resource, time, political, and legislative challenges.Conclusion: Stem cell research presents a novel therapeutic method that could alleviate the burden of non-communicable diseases. Early research indicates that it is efficacious, feasible, and safe, with potential clinical, economic, and social benefits. However, several barriers, including ethical concerns, financial constraints, and human resource limitations, still need to be addressed.
