The article focuses on a report related to tetanus cases after voluntary medical male circumcision (VMMC) for HIV prevention in eastern and southern Africa from 2012 to 2015. Topics include decreasing the risk for female-to-male HIV transmission by VMMC, applying traditional remedies containing substances contaminated with spores of Clostridium tetani, and delays in seeking medical attention, access to tetanus immune globulin, and quality of supportive care as factors affecting survival.