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Are hospital-based Emergency Medical Services effective and efficient; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background: Effective Emergency Medical Services (EMS) aim to provide timely care for medical emergencies, including pre-hospital care, transfer, and in-hospital treatment. A well-coordinated, designed, and locally appropriate system is crucial …

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How can Community Health Workers be used to empower communities; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background: Community empowerment enables people to increase control over their lives and decisions, implying ownership and action towards social and developmental change. Effective empowerment strategies build on authentic participation, autonomy …

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How safe is the practice of Reflexology; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background: Reflexology is a therapeutic method of relieving pain by stimulating predefined pressure points on the feet and hands. While its popularity has increased, the safety of reflexology has not …

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What are the best methods for involving patients in health system decision-making in Uganda; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background: The involvement of patients and the community in health care is widely acknowledged for its potential to improve the availability and relevance of health services and to promote participative …

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What are the effects and guidelines of mass immunization of health workers against Hepatitis B; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background: Hepatitis B is a major global occupational health hazard, with healthcare workers having a higher prevalence of HBV infection than the general population. Vaccination is recommended to reduce the …

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What does policy implementation monitoring entail; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background:Monitoring is essential for policymakers, government officials, development managers, and civil society to learn from past experiences, improve service delivery and plan and allocate resources. In addition, it helps to …

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What is the appropriate malaria treatment for a low-income endemic country like Uganda; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background: The treatment of malaria in endemic, low-income countries is complicated by increasing resistance to anti-malarial medicines and challenges in accessing these medicines. The World Health Organization (WHO) has issued …

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What should be included in an optimal package of interventions to prevent the spread of HIV and manage HIV/AIDS; A Rapid Response Brief
ACRES
2010
brief
Health Research

Background: HIV/AIDS prevention and management requires a multi-pronged approach, including clinical and public health interventions.Rapid Response Question: What should be included in an optimal package of interventions to prevent the …

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Are herbal photolarvicides efficient and safe to use in vector management; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The resurgence of interest in larvicides for vector control, particularly in combating malaria, is driven by research demonstrating their effectiveness in reducing mosquito populations and malaria infection rates. Recent …

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Can decentralization of health services improve health service delivery in Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many developing countries face challenges in providing quality and equitable healthcare, especially to marginalized populations. Decentralization, a political reform aimed at reducing central influence and increasing local autonomy, has …

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References (4020)

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P-A12âAssessing quality of HIV treatment in the United States Military HIV Research Program/President's Emergency Plan for AIDS Relief (PEPFAR)-supported programs in Africa
Hughes Lindsay, Hamm Tiffany, Crawford Keith, Lenneman Tessa, Kibuuka Hannah, Maswai Jonah, Clinkscales Jessica, Robb Merlin, Michael Nelson
2014
Journal, Article
Health Research

Following rapid scale up of ART, attention is now focused on improving quality of care and identifying populations and interventions to maximize impact and long-term effectiveness. Viral load, considered the …

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Impact of Exposure to Long Lasting Insecticide Treated Nets on Mosquito Survival and Behaviour at the Net Interface in Insecticide Susceptible and Resistant Strains of the Afrotropical Anopheles Mosquito
Hughes Angela Jane
2018
Dissertation
Health Research

The central role of long-lasting insecticidal nets (LLINs) in malaria prevention in Africa is threatened by insecticide resistance. Little is known about mosquito behaviour near, or of the importance of …

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Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women
Hughes E, Mwebaza N, Huang LS, Kajubi R, Nguyen V, Nyunt MM, Orukan F, Mwima MW, Parikh S, Aweeka F
2020
Journal, Article
Health Research

Background: The choice of malaria treatment for HIV-infected pregnant women receiving efavirenz-based antiretroviral therapy must consider the potential impact of drug interactions on antimalarial exposure and clinical response. The aim …

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Piperaquine Exposure Is Altered by Pregnancy, HIV, and Nutritional Status in Ugandan Women
Zhang N, Kakuru A, Havlir D, Kamya M, Natureeba P, Dorsey G, Rosenthal P J, Huang L, Muhindo M, Hughes E and others...
2020
Journal, Article
Health Research

Dihydroartemisinin-piperaquine (DHA-PQ) provides highly effective therapy and chemoprevention for malaria in pregnant African women. PQ concentrations of >10.3âng/ml have been associated with reduced maternal parasitemia, placental malaria, and improved birth …

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Neurosurgical Decision-Making and Ethical Considerations in the Treatment of Traumatic Brain Injury
Hughes Jasmine
2022
Dissertation
Health Research

Globally, disparities in the availability of surgical care are prevalent, and for specialty care such as neurosurgery, services are typically scarce to non-existent. In low-and-middle-income countries, most medical centers have …

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Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women
Dorsey G., Rosenthal P.J., Hughes E., Wallender E., Kajubi R., Jagannathan P., Ochieng T., Kakuru A., Kamya M.R., Clark T.D. and others...
2022
Journal, Article
Health Research

BACKGROUND: Intermittent preventive treatment with monthly dihydroartemisinin-piperaquine (DHA-PQ) is highly effective at preventing both malaria during pregnancy and placental malaria. Piperaquine prolongs the corrected QT interval (QTc), and it is …

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Long-Term virological outcomes, failure and acquired resistance in a large cohort of Ugandan children
Kityo C, Mugyenyi P, Huibers M H.W, Boerma R S, Kaudha E, Sigaloff K C.E, Balinda S N, Bertagnolio S, Nakanjako R, Calis J C.J and others...
2019
Journal, Article
Health Research

Objectives: To evaluate long-term virological failure (VF) and drug resistance among HIV-infected Ugandan chil-dren on first-line ART.Methods: In a multicentre prospective cohort study, viral load (VL) and drug resistance mutations …

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PRECISION PUBLIC HEALTH AND PANDEMIC PREPAREDNESS: QUANTIFYING TRAVEL TIME TO HEALTH CARE AND LOCATIONS AT RISK FOR PATHOGEN TRANSMISSION
et al, Hulland E., Wiens K., Shirude S., Bell B., Rabinowitz P., Institute for Health Metrics, Evaluation Seattle W. A. United States
2019
Journal, Article
Health Research

AFRICAN DEVELOPMENT Abstract: Infectious disease threats exist even in places without evidence of past events, and without clear preparedness plans to prevent, detect, and respond to such threats, outbreaks can …

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Mechanisms of paediatric trauma at a rural hospital in Uganda.
Hulme P.
2010
Journal, Article
Health Research
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Mechanisms of trauma at a rural hospital in Uganda
Hulme P.
2010
Journal, Article
Health Research
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