Digital Evidence Base

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Improving collaboration between primary care and mental health services
Arroll Bruce, Kates Nick, Currie Elizabeth, Hanlon Charlotte, Gask Linda, Klasen Henrikje, Meadows Graham, Rukundo Godfrey, Sunderji Nadiya, Ruud Torleif, Williams Mark
2019
DOI: 10.1080/15622975.2018.1471218

Objective: Previous guidelines and planning documents have identified the key role primary care providers play in delivering mental health care, including the recommendation from the WHO that meeting the mental …

Abstract
Report by Kathi
Kathi
2015
Abstract
Mitochondrial DNA sequence divergence and diversity of Glossina fuscipes fuscipes in the Lake Victoria basin of Uganda: implications for control
Hyseni C, Okedi LM, Caccone A, Aksoy S, Masembe C, Kato AB, Ouma JO
2015
DOI: 10.1186/s13071-015-0984-1

Background: Glossina fuscipes fuscipes is the main vector of African Trypanosomiasis affecting both humans and livestock in Uganda. The human disease (sleeping sickness) manifests itself in two forms: acute and …

Abstract
Population genetic structure and temporal stability among Trypanosoma brucei rhodesiense isolates in Uganda
Kato CD, Matovu E, Nanteza A, Alibu VP, Mugasa CM
2016
DOI: 10.1186/s13071-016-1542-1

Background: The population structure and role of genetic exchange in African trypanosomes have been previously analyzed albeit with contradictory findings. To further investigate the role of genetic polymorphism on the …

Abstract
The role of cytokines in the pathogenesis and staging of Trypanosoma brucei rhodesiense sleeping sickness
Nanteza Ann, Matovu Enock, Alibu Vincent P., Kato Charles D., Mugasa Claire M.
2016

MEDLINE Abstract: Human African trypanosomiasis due to Trypanosoma brucei rhodesiense is invariably fatal if untreated with up to 12.3 million people at a risk of developing the disease in Sub-Saharan …

Abstract
Relationship between Trypanosoma brucei rhodesiense genetic diversity and clinical spectrum among sleeping sickness patients in Uganda
Matovu E, Nanteza A, Kato C D, Mugasa C M, Alibu V P
2017
DOI: 10.1186/s13104-017-2860-x

ObjectiveHuman African trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense in East and southern Africa is reported to be clinically diverse. We tested the hypothesis that this clinical diversity is associated …

Abstract
Project Brief for introduction of a new non-toxic Biological Larvicide to Control Mosquitoes in Uganda
Kato Agapitus Babumba
2018

Innovation and Development Corporation (abbreviated as InRAD for purposes of this document) is desirous of introducing to Uganda a new non-toxic powder (larvicide) to combat and destroy Mosquito Larvae. The …

Abstract
Plasma Neuron-Specific Enolase is not a reliable biomarker for staging Trypanosoma brucei rhodesiense sleeping sickness patients
Kato C.D., Twesigye D., Alibu V.P., Nanteza A., Nsubuga J., Mugasa C.M., Matovu E.
2022
DOI: 10.1186/s13104-022-05981-w

OBJECTIVE: Currently, the only available staging criterion for T. b. rhodesiense requires a lumber puncture to collect and later examine cerebrospinal fluid (CSF). This study examined the potential of plasma …

Abstract
The human microbiome and its link in prostate cancer risk and pathogenesis
Joloba M., Reynolds S.J., Katongole P., Sande O.J., Niyonzima N.
2020
DOI: 10.1186/s13027-020-00319-2

There is growing evidence of the microbiome's role in human health and disease since the human microbiome project. The microbiome plays a vital role in influencing cancer risk and pathogenesis. …

Abstract
IL-6 and IL-8 cytokines are associated with elevated prostate-specific antigen levels among patients with adenocarcinoma of the prostate at the Uganda Cancer Institute
Ssebambulidde K, Reynolds S J, Joloba M, Atuheirwe M, Kajumbula H, Orem J, Niyonzima N, Kalungi S, Katongole P, Sande O J, Nabweyambo S
2022
DOI: 10.2217/fon-2021-0683

Background: The possible clinical application of specific cytokines and chemokines contributing to tumorigenesis and the clinical outcome of several cancers has been reported. However, less invasive and easily applicable biomarkers …

Abstract
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