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The Influence of Pregnancy on PrEP uptake and Adherence Amongst HIV-Negative High-Risk Young Women in Kampala, Uganda: A Qualitative Assessment
Homsy J., Joshi S., Namuddu C., Kasujja F.X., Mirembe M., Seeley J., King R.
2022
DOI: 10.1101/2022.04.12.22273506

Background: Pregnant young women who engage in high-risk sexual activity are at elevated biological and social risk for HIV acquisition. PrEP serves as an effective means of HIV prevention, including …

Abstract
Prevalence and factors associated with behavioural problems in children with epilepsy attending Mulago hospital, Uganda: A cross-sectional study
Rujumba J, Bangirana P, Kakooza-Mwesige A, Josias KS
2021
DOI: 10.1016/j.seizure.2021.04.003

Purpose: : To determine the prevalence of behavioural problems and the associated factors in children with epilepsy (CWE).Methods: : This was a cross-sectional study conducted at Mulago National Referral Hospital, …

Abstract
Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda
Kyeyune F, Nankya I, Quinones-Mateu ME, Nalukwago S, Kityo CM, Joussef-Pina S, Baseke J, Rwambuya S, Winner D, Chervenak K, Thiel B, Asaad R, Dobrowolski C, Luttge B, Lawley B, Boom WH, Karn J
2022
DOI: 10.1186/s12977-022-00587-3

Background Our understanding of the peripheral human immunodeficiency virus type 1 (HIV-1) reservoir is strongly biased towards subtype B HIV-1 strains, with only limited information available from patients infected with …

Abstract
Pioneering water quality data on the Lake Victoria watershed: effects on human health
Jovanelly TJ, Johnson-Pynn J, Okot-Okumu J, Nyenje R, Namaganda E
2015
DOI: 10.2166/wh.2015.001

Four forest reserves within 50 km of Kampala in Uganda act as a critical buffer to the Lake Victoria watershed and habitat for local populations. Over a 9-month period we …

Abstract
Breast self-examination among female clients in a tertiary hospital in Eastern Uganda
Iramiot J S, Joyce C, Ssenyonga L V.N
2020
DOI: 10.1016/j.ijans.2019.100186

BackgroundBreast self-examination is a widely accepted, inexpensive and non-complex screening method for breast cancer because it does not entail complex technical training and therefore a more practical approach in a …

Abstract
Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective
JT Schwartze, M Havenga, WAM Bakker, AC Bradshaw, SA Nicklin
2022
DOI: 10.1007/s00109-022-02208-0

Despite the development of novel pharmacological treatments, cardiovascular disease morbidity and mortality remain high indicating an unmet clinical need. Viral gene therapy enables targeted delivery of therapeutic transgenes and represents …

Abstract
Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphoma in Uganda
Reynolds SJ, Juan R, Otim I, Nabalende H, Legason ID, Ogwang MD, Ndugwa CM, Marshall V, Whitby D, Goedert JJ, Engels EA, Bhatia K, Lenardo MJ, Mbulaiteye SM
2018
DOI: 10.1016/j.canep.2017.12.004

Background: Epstein-Barr virus (EBV) causes endemic Burkitt lymphoma (eBL). EBV control was improved by magnesium (Mg2+) supplementation in XMEN, an X-linked genetic disease associated with Mg2+ deficiency, high circulating EBV …

Abstract
Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial
Nyehangane D, Mwanga-Amumpaire J, Mulogo EM, Fall G, Juan-Giner A, Kimathi D, Grantz KH, Hamaluba M, Kazooba P, Njuguna P, Dia M, Bob NS, Monath TP, Barrett AD, Hombach J, Ampeire I, Karanja HK, Cummings DAT, Bejon P, Warimwe GM, Grais RF
2021

Background Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD substrain vaccine. We …

Abstract
Socio-economic and demographic factors associated with never having tested for HIV among sexually active men across the four administrative regions of Uganda
Jude O, Nelson O, Katagwa I
2021
DOI: 10.1186/s12889-021-12384-2

Background HIV testing among men is paramount in the prevention, diagnosis, and treatment of HIV. There is limited literature in understanding the socio-economic and demographic factors associated with never having …

Abstract
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