Digital Evidence Base

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Extended prophylaxis with nevirapine and cotrimoxazole among HIV-exposed uninfected infants is well tolerated
Aizire J, Fowler M G, Wang J, Shetty A K, Stranix-Chibanda L, Kamateeka M, Brown E R, Bolton S G, Musoke P M, Coovadia H
2012
DOI: 10.1097/QAD.0b013e32834e892c

AbstractObjectiveâNevirapine and cotrimoxazole are associated with hematologic toxicities and skinrash. Safety of their concurrent use for prophylaxis over extended periods among HIV-exposeduninfected infants has not been previously assessed.DesignâSecondary data analysis …

Abstract
Inner preputial flap as tunica albuginea replacement in the management of previously untreated fracture of the penis
Bhat A, Sharma B, Dawan M, Saxena G
2010

To assess the efficacy of an inner preputial skin flap as replacement for the tunica albuginea of the corpus cavernosum after excision of fibrous plaque. Patients and Methods In this …

Abstract
Domestic violence in a post-conflict African setting : a study of gender and role on personality, coping styles, attitudes to coercion and self-reported victimization in a Ugandan urban sample
Karugahe Wilbur
2016

Domestic violence has been gradually increasing globally with developing countries across Sub-Saharan Africa being the most affected (WHO, 2013). Uganda, in particular, ranks highest in relation to the incidence of …

Abstract
Project Brief for introduction of a new non-toxic Biological Larvicide to Control Mosquitoes in Uganda
Kato Agapitus Babumba
2018

Innovation and Development Corporation (abbreviated as InRAD for purposes of this document) is desirous of introducing to Uganda a new non-toxic powder (larvicide) to combat and destroy Mosquito Larvae. The …

Abstract
Virologic Response to First-line Efavirenz-or Nevirapine-based Antiretroviral Therapy in HIV-infected African Children
Gibb D.M., Spyer M., Musiime V., Bakeera-Kitaka S., Mhute T., Kekitiinwa A., Walker A.S., Szubert A.J., Katuramu R., Senfuma O.
2017
DOI: 10.1097/INF.0000000000001505
Abstract
Trends and level of control of hypertension among adults attending an ambulatory HIV clinic in Kampala, Uganda: A retrospective study
Kalyesubula R, Kayongo A, Semitala F C, Muhanguzi A, Katantazi N, Ayers D, Forrest J I, Mills E J
2016
DOI: 10.1136/bmjgh-2016-000055

Background: With an ageing HIV-positive population,sub-Saharan Africa is now facing a dual epidemic ofcommunicable and non-communicable diseases(NCDs). This study aimed to assess trends in theprevalence of hypertension and factors associated …

Abstract
Hunger, waiting time and transport costs: Time to confront challenges to ART adherence in Africa
Moyo S., Hardon A. P., Akurut D., Comoro C., Ekezie C., Irunde H. F., Gerrits T., Kglatwane J., Kinsman J., Kwasa R., Maridadi J., Moroka T. M., Nakiyemba A., Nsimba S., Ogenyi R., Oyabba T., Temu F., Laing R.
2007
DOI: 10.1080/09540120701244943

Adherence levels in Africa have been found to be better than those in the US. However around one out of four ART users fail to achieve optimal adherence, risking drug …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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