Digital Evidence Base

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Hazardous alcohol consumption and alcohol-related problems are associated with unknown and HIV-positive status in fishing communities in Uganda
Kiene SM, Sileo KM, Dove M, Kintu M
2019
DOI: 10.1080/09540121.2018.1497135

In Uganda, alcohol consumption is associated with higher HIV prevalence. However, research is needed to better understand how different patterns of alcohol consumption and alcohol-related problems may drive this association. …

Abstract
TGF-β : A key player in age-related loss of skin innate immunity
Gutierrez-Mateyron E., Bobé P.
2021
DOI: 10.1051/medsci/2020283
Abstract
Effect of airtime incentives on response and cooperation rates in non-communicable disease interactive voice response surveys: randomised controlled trials in Bangladesh and Uganda
Gibson DG, Pariyo GW, Wosu AC, Ali J, Ahmed S, Labrique AB, Rutebemberwa E, Hyder AA, Khan IA, Flora MS
2019
DOI: 10.1136/bmjgh-2019-001604

Background The global proliferation of mobile phones offers opportunity for improved non-communicable disease (NCD) data collection by interviewing participants using interactive voice response (IVR) surveys. We assessed whether airtime incentives …

Abstract
Assessing the performance of medical personnel involved in the diagnostic imaging processes in mulago hospital, kampala, Uganda
Kawooya Michael G., Pariyo George, Malwadde Elsie Kiguli, Byanyima Rosemary, Kisembo Harrient
2012

MEDLINE Abstract: OBJECTIVES: Uganda, has limited health resources and improving performance of personnel involved in imaging is necessary for efficiency. The objectives of the study were to develop and pilot …

Abstract
Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays
KimudaMagambo Phillip, Laming Dustin, Hoppe Heinrich C., Tastan Bishop Ãzlem
2019

MEDLINE Abstract: Pteridine reductase 1 (PTR1) is a trypanosomatid multifunctional enzyme that provides a mechanism for escape of dihydrofolate reductase (DHFR) inhibition. This is because PTR1 can reduce pterins and …

Abstract
'I am the master key that opens and locks': Presentation and application of a conceptual framework for women's and girls' empowerment in reproductive health
Makumbi F, Kibira SPS, Karp C, Wood SN, Galadanci H, Omoluabi E, Shiferaw S, Seme A, Tsui A, Moreau C
2020
DOI: 10.1016/j.socscimed.2020.113086

Rationale: A renewed focus on women's and girls' empowerment in the era of Sustainable Development Goals reflects the belief that empowerment is central to health and development. Sexual and reproductive …

Abstract
Quality of Life among Obstetric Fistula Patients at Kitovu Mission Hospital: A Health Facility-Based Cross-Sectional Study in Masaka District, Uganda
Atuhairwe C, Taremwa IM, Kakembo S
2020
DOI: 10.1155/2020/7953915

Background. Obstetric fistula (OF) remains a silent neglected maternal challenge associated with devastating life consequences. Living with OF presents far-reaching physical, social, psychosocial, and emotional concerns, which negatively impact a …

Abstract
The HIV-associated tuberculosis epidemic--when will we act?
Corbett Elizabeth L., Lawn Stephen D., Zachariah Rony, Harries Anthony D., Santos-Filho Ezio T., Chimzizi Rhehab, Harrington Mark, Maher Dermot, Williams Brian G., De Cock Kevin M.
2010
DOI: 10.1016/S0140-6736(10)60409-6

The article looks at the global prevalence of HIV-associated tuberculosis, particularly in sub-Saharan Africa. The authors call for more aggressive means to diagnose and treat HIV infection and propose urgent …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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