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Annual trends of human brucellosis in pastoralist communities of south-western Uganda: a retrospective ten-year study
Bazira J, Asiimwe BB, Rutebemberwa E, Makumbi F, Kansiime C, Mugisha A
2015
DOI: 10.1186/s40249-015-0072-y

Background: Human brucellosis is prevalent in both rural and urban Uganda, yet most cases of the disease in humans go unnoticed and untreated because of inaccurate diagnosis, which is often …

Abstract
HIV Drug Resistance Mutations in Non-B Subtypes After Prolonged Virological Failure on NNRTI-Based First-Line Regimens in Sub-Saharan Africa
Kityo C, Mugyenyi P, Nankya I, Ndashimye E, Easterbrook PJ, Bertagnolio S, Wools-Kaloustian K, Walker AS, Thompson J, Hoppe A, Warambwa C, Mambule I, van Oosterhout JJ, Paton NI
2017
DOI: 10.1097/QAI.0000000000001285

Objective: To determine drug resistance mutation (DRM) patterns in a large cohort of patients failing nonnucleoside reverse transcriptase inhibitor (NNRTI)-based first-line antiretroviral therapy regimens in programs without routine viral load …

Abstract
Comparison of HIV incidence in simulated vaccine efficacy trials and observational cohorts using propensity scores in key populations in Uganda
Abaasa A., Asiki G., Kaleebu P., Todd J., Mayanja Y., Price M., Fast P.E.
2021
DOI: 10.1002/jia2.25659

Background: The design of HIV prevention clinical trials in the context of effective preventive methods is a challenge. Alternate designs, including using non-randomised 'observational control arms' have been proposed. We …

Abstract
Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions
Tobian AAR, Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S
2016
DOI: 10.1111/trf.13594

BACKGROUNDLittle data are available on bacterial contamination (BC) of platelet units or acute transfusion reactions to platelet transfusions (PTs) in sub-Saharan Africa (SSA).STUDY DESIGN AND METHODSThis prospective, observational study evaluated …

Abstract
Sulfamethoxazole Levels in HIV-Exposed Uninfected Ugandan Children
Serwadda D, Reynolds SJ, Kasule J, Gabriel EE, Anok A, Neal J, Eastman RT, Penzak S, Newell K, Duffy PE, Hobbs CV
2018
DOI: 10.4269/ajtmh.17-0933

Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis in HIV-uninfected, exposed (HUE) children variably reduces clinical malaria burden despite antifolate resistance, but data regarding achieved serum levels and adherence are lacking. Serum samples from 70 …

Abstract
Prevalence, determinants and impact of unawareness about the health consequences of tobacco use among 17 929 school personnel in 29 African countries
Agaku I T, Filippidis F T
2014
DOI: 10.1136/bmjopen-2014-005837

Objectives To assess prevalence, determinants and impact of unawareness about the health consequences of tobacco use among school personnel in Africa.Design Cross-sectional surveys.Setting Twenty-nine African countries.Participants Representative samples of school …

Abstract
Lira technique after medium followup. results of a new minimal invasive procedure in ventral hernia repair
Gómez-Menchero J., Gila Bohorquez A., De la Herranz P., Ramirez J.L.G.
2021
DOI: 10.1093/bjs/znab395.140

Aim: LIRA technique (Laparoscopic Intracorporeal Rectus Aponeuroplasty) was described in 2018 in order to reduce the tension in the midline as an alternative to defect closure (CD) in Laparoscopic Ventral …

Abstract
Religiosity and Adherence to Antiretroviral Therapy Among Patients Attending a Public Hospital-Based HIV/AIDS Clinic in Uganda
Muliira JK, Kisenyi RN, Ayebare E
2013
DOI: 10.1007/s10943-011-9473-9

In Uganda, the prevalence of non-adherence to antiretroviral therapy (ART) by HIV/AIDS patients remains high and sometimes this is blamed on patients' religious behavior. A descriptive design was used to …

Abstract
Rare breast malignancy subtypes: A cytological, histological, and immunohistochemical correlation
Kaur Manmeet, Kaur Kanwardeep Tiwana, Singla Nisha
2019

Background: Breast malignancies encompass various subtypes which differ in their clinical presentations, outcomes, and response to the treatment regimens. Thus, a proper histological diagnosis and a special mention of the …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
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