Digital Evidence Base

Trusted Knowledge for Informed Decisions

Filters
SDGs
Priority Areas
Research Outcomes
Document Type
Year
4019 results found
Show:
Escherichia coli, a pathogen under fire from the news
Grp Pathologie Infect Pediat, Cohen R, Raymond J, Gendrel D, Bingen E
2012

Escherichia coli is both a gastrointestinal tract commensal and a major pathogen. In recent years, E. coli is under lire from the news due to a better understanding of pathogenic …

Abstract
Trends in hepatitis B virus testing practices and management in HIV clinics across sub-Saharan Africa
Ocama P, IeDEA Collaboration, Coffie PA, Egger M, Vinikoor MJ, Zannou M, Diero L, Patassi A, Kuniholm MH, Seydi M, Bado G, Andersson MI, Messou E, Minga A, Easterbrook P, Anastos K, Dabis F, Wandeler G
2017
DOI: 10.1186/s12879-017-2768-z

Background: Approximately 8% of HIV-infected individuals are co-infected with hepatitis B virus (HBV) in sub-Saharan Africa (SSA). Knowledge of HBV status is important to guide optimal selection of antiretroviral therapy …

Abstract
Potential Roles of Mhealth for Community Health Workers: Formative Research With End Users in Uganda and Mozambique
Kallander K, InSCALE Study Grp, Thondoo M, Strachan DL, Nakirunda M, Ndima S, Muiambo A, Hill Z
2015
DOI: 10.2196/mhealth.4208

Background: Community health workers are reemerging as an essential component of health systems in low-income countries. However, there are concerns that unless they are adequately supported, their motivation and performance …

Abstract
Availability, prices and affordability of UN Commission's lifesaving medicines for reproductive and maternal health in Uganda
Kibira D, Kitutu F E, Merrett G B, Mantel-Teeuwisse A K
2017
DOI: 10.1186/s40545-017-0123-9

BackgroundUganda was one of seven countries in which the United Nations Commission on Life Saving Commodities (UNCoLSC) initiative was implemented starting from 2013. A nationwide survey was conducted in 2015 …

Abstract
Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial
A5263 AMC066 Protocol Team, Krown SE, Moser CB, MacPhail P, Matining RM, Godfrey C, Caruso SR, Hosseinipour MC, Samaneka W, Nyirenda M, Busakhala NW, Okuku FM, Kosgei J, Hoagland B, Mwelase N, Oliver VO, Burger H, Mngqibisa R, Nokta M, Campbell TB, Borok MZ
2020
DOI: 10.1016/S0140-6736(19)33222-2

Background Optimal treatment regimens for AIDS-associated Kaposi sarcoma, a frequent contributor to morbidity and mortality among people with HIV, have not been systematically evaluated in low-income and middle-income countries, where …

Abstract
Associations between social support, psychological well-being, decision making, empowerment, infant and young child feeding, and nutritional status in Ugandan children ages 0 to 24months
Wu M, Ickes SB, Mandel MP, Roberts AC
2018
DOI: 10.1111/mcn.12483

Maternal capabilitiesqualities of mothers that enable them to leverage skills and resources into child healthhold potential influence over mother's adoption of child caring practices, including infant and young child feeding. …

Abstract
Pneumonia in HIV-exposed and Infected Children and Association With Malnutrition
Kiwanuka J, Kumbakumba E, Kabakyenga J, Iroh Tam P.-Y, Wiens M O, Moschovis P P
2018
DOI: 10.1097/INF.0000000000001971

We evaluated the association between HIV exposed-uninfected (HEU) status, malnutrition and risk of death in Ugandan children hospitalized with pneumonia. Both HIV exposure and infection were associated with lower anthropometric …

Abstract
A systematic review of modeling and simulation approaches in designing targeted treatment technologies for Leukemia Cancer in low and middle income countries
Ibingira C., Muwonge H., Kiwumulo H.F., Kirabira J.B., Ssekitoleko R.T.
2021
DOI: 10.3934/mbe.2021404

Virtual experimentation is a widely used approach for predicting systems behaviour especially in situations where resources for physical experiments are very limited. For example, targeted treatment inside the human body …

Abstract
Apabetalone downregulates fibrotic, inflammatory and calcific processes in renal mesangial cells which may contribute to reduced cardiac events observed in ckd patients
Gilham D., Fu L., Rakai B., Wasiak S., Tsujikawa L., Halliday C., Sarsons C., Stotz S., Jahagirdar R., Johansson J., Sweeney M., Wong N., Kalantar-Zadeh K., Kulikowski E.
2021
DOI: 10.1093/ndt/gfab078.008

BACKGROUND AND AIMS: Major adverse cardiac events (MACE) remain a leading cause of mortality in chronic kidney disease (CKD). Apabetalone is an orally available inhibitor of bromodomain & extraterminal (BET) …

Abstract
AI Research Assistant
AI-powered research assistance. Uses the Digital Evidence Base as the Knowledge source.