Urban-rural differences in immune responses to mycobacterial and tetanus vaccine antigens in a tropical setting: A role for helminths?

Several vaccines elicit lower efficacy or impaired immune responses in rural compared to urban settings, and intropical low-income countries compared to high-income countries. An unresolved hypothesis is that im-munomodulation by …

Anti-malarial Antibody Responses and Applications for Assessing Malaria Exposure

This dissertation describes the discovery of highly informative serologic biomarkers of recent exposure to Plasmodium falciparum, the most deadly species causing malaria. An innovative approach that combined detailed individual-level exposure …

Erratum: Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial (The Lancet (2010) 375(9724) (1447â1456) (S0140673610603078) (10.

Extraction of the lateral incisors to treat maxillary protrusion: Quantitative evaluation of the stomatognathic functions

To treat morphological abnormalities, impaction, and severe malposition of the teeth, the lateral incisors are sometimes extracted, followed by orthodontic space closure. This procedure often requires special consideration, not only …

Early Alcohol Use and Problem Drinking among Students in Zambia and Uganda

Excessive alcohol use is a serious public health concern worldwide; but less attention has been given to the prevalence; risk and protective factors; and consequences of early alcohol use in …

Survival and HIV-Free Survival Among Children Aged â¤3 Years - Eight Sub-Saharan African Countries, 2015-2017

Although mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) is preventable through antiretroviral treatment (ART) during pregnancy and postpartum, the Joint United Nations Programme on HIV/AIDS (UNAIDS) estimates that 160,000 …

An Epidemiologic Investigation of Physical Activity and Breast Cancer Risk in Africa

Background: Physical activity (PA) is modifiable and linked to decreased breast cancer risk but its impact has not been investigated among indigenous African populations.Methods: From 2011 to 2013, 558 cases …

Psychological contract, engagement and employee discretionary behaviours Perspectives from Uganda

Purpose - The purpose of this paper is to examine the mediation effect of employee engagement on the relationship between employer obligations, employee obligations and state of the psychological contract …

Only connect â the role of PLHIV group networks in increasing the effectiveness of Ugandan HIV services...people living with HIV

In recent years, Uganda has experienced rapid growth in networked groups of people living with HIV (PLHIV) who provide support, engage in advocacy, treatment and care and raise the profile …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …