HIV Drug Resistance Among Children Initiating First-Line Antiretroviral Treatment in Uganda

Background: There are limited data on primary human immunodeficiency virus drug resistance (HIVDR) in pediatric populations. This study aimed to assess the prevalence of primary HIVDR and associated risk factors …

HIV Drug Resistance Mutations in Non-B Subtypes After Prolonged Virological Failure on NNRTI-Based First-Line Regimens in Sub-Saharan Africa

Objective: To determine drug resistance mutation (DRM) patterns in a large cohort of patients failing nonnucleoside reverse transcriptase inhibitor (NNRTI)-based first-line antiretroviral therapy regimens in programs without routine viral load …

Pretreatment HIV drug resistance results in virological failure and accumulation of additional resistance mutations in Ugandan children

Background: Pretreatment HIV drug resistance (PDR) can impair virological response to ART, jeopardizing effective treatment for children.Methods: Children aged <12 years initiated first-line ART in Uganda during 2010-11. Baseline and …

Lymphoid tissue fibrosis is associated with impaired vaccine responses

Vaccine responses vary by geographic location. We have previously described how HIV-associated inflammation leads to fibrosis of secondary lymph nodes (LNs) and T cell depletion. We hypothesized that other infections …

Eating away from home is associated with overweight and obesity among Ugandan adults: the 2014 Uganda non-communicable disease risk factor survey

BACKGROUND/OBJECTIVES: We investigated the associations between eating away from home (EAFH) and overweight and obesity among Ugandan adults using the 2014 Uganda non-communicable disease risk factor survey. SUBJECTS/METHODS: In total, …

Biofilm formation of candida spp. Isolated from the vagina and antibiofilm activities of lactic acid bacteria on the these candida isolates

Background: In this study, it was aimed to investigate the effects of bacterial cells and cell-free filtrates of Lactobacillus acidophilus 8MR7 and Lactobacillus paracasei subspecies paracasei 10MR8 on the biofilm …

Knowledge, attitudes and practices regarding emergency contraceptive pills among female undergraduate students of Makerere University, Uganda

Prevalence of behavioral disorders and attention deficit/hyperactive disorder among school going children in Southwestern Uganda

Background: Disruptive Behavioral Disorders (DBDs) and Attention Deficit/Hyperactivity Disorder (ADHD)are chronic, impairing, and costly child and adolescent mental health challenges which, when untreated, can result in disruptions in school performance, …

Utilizing a family-based economic strengthening intervention to improve mental health wellbeing among female adolescent orphans in Uganda

BackgroundIt is estimated that almost 20% of the world's adolescents have experienced or are experiencing a mental health problem. Several factors have been associated with the onset of adolescent mental …

Using a structured approach to evaluate ICT4D: Healthcare delivery in Uganda

Using a case from the healthcare delivery sector, we demonstrate how a structured evaluationapproach can facilitate the measurement of actual ICT contributions in various contexts.Typically, such are intricate due to …