Two simple replacements for the Triage Early Warning Score to facilitate the South African Triage Scale in low resource settings

Background: The South African Triage Scale (SATS) requires the calculation of the Triage Early Warning Score (TEWS), which takes time and is prone to error.Aim: to derive and validate triage …

The use of placebo in a trial of rectal artesunate as initial treatment for severe malaria patients en route to referral clinics: ethical issues

Placebo-controlled trials are controversial when individuals might be denied existing beneficial medical interventions. In the case of malaria, most patients die in rural villages without healthcare facilities. An artesunate suppository …

Health system effects of implementing integrated community case management (iCCM) intervention in private retail drug shops in South Western Uganda: A qualitative study

Background Intervening in private drug shops to improve quality of care and enhance regulatory oversight may have health system effects that need to be understood before scaling up any such …

Can malaria rapid diagnostic tests by drug sellers under field conditions classify children 5years old or less with or without Plasmodium falciparum malaria? Comparison with nested PCR analysis

BackgroundMalaria rapid diagnostic tests (RDTs) available as dipsticks or strips, are simple to perform, easily interpretable and do not require electricity nor infrastructural investment. Correct interpretation of and compliance with …

Towards a functioning retail health market: evaluating the integrated community case management intervention for pediatric febrile illness in drug shops in rural south western uganda

Objectives: This thesis examined the health systems effects of implementing the integrated Community Case Management (iCCM) intervention for paediatric febrile illnesses in a retail health market in South Western Uganda. …

Aflatoxin levels in common foods of South Western Uganda: a risk factor to hepatocellular carcinoma

Prolonged exposure to aflatoxins by humans and animals leads to adverse effects to the various body systems of affected individuals including death. Studies have linked aflatoxins to hepatocellular carcinoma (HCC). …

Role of Conventional Myelography in Diagnosis and Treatment of Degenerative Spine Disease in Low-Income Communities: Prospective Study

Causes, clinical presentation, management, and outcomes of chronic subdural hematoma at Mbarara Regional Referral Hospital

OBJECTIVE Causes, clinical presentation, management, and outcomes of chronic subdural hematoma (CSDH) in low- and middle-income countries are not well characterized in the literature. Knowledge regarding these factors would be …

Pharmacokinetics of lopinavir-ritonavir with and without nonnucleoside reverse transcriptase inhibitors in Ugandan HIV-infected adults

Therapeutic immunization in HIV infected Ugandans receiving stable antiretroviral treatment: A Phase I safety study

Therapeutic immunizations in HIV infection may boost immunity during antiretroviral treatment. We report on the first therapeutic vaccine trial in Uganda, Africa. This open label Phase I trial was designed …