Impact of recurrent outbreaks of Ebola virus disease in Africa: a meta-analysis of case fatality rates

Objectives: Between 2010 and 2020, Africa witnessed several outbreaks of Ebola virus disease (EVD), each presenting with varying case fatality rate (CFR) and other socio-economic impacts. This study aims to …

Prevalence and factors associated with sexual violence among women aged 15-49 years in rural Uganda: evidence from the Uganda Demographic and Health Survey 2016

Objectives: Sexual violence is a serious global health problem with short- and long-term physical, mental, and reproductive adverse effects. This study aimed to determine the prevalence and factors associated with …

Reflecting on the First Two COVID-19 Deaths in Uganda: A Public Health Perspective

A study on inclusion of leprosy in the curricula of pre-service health training institutions in Uganda

Objective: To establish the categories of pre-service health training institutions in Uganda that still maintain leprosy in their curricula and how leprosy training is organised.Materials and methods: A structured questionnaire …

'Children will always be children': Exploring perceptions and experiences of HIV-positive children who may not take their treatment and why they may not tell

HIV-positive children and young people may face substantial social barriers to maintaining appropriate levels of adherence to antiretroviral therapy (ART) during childhood and adolescence. In this paper, we focus on …

Dolutegravir pharmacokinetics during co-Administration with either artemether/lumefantrine or artesunate/amodiaquine

Background: In sub-Saharan Africa, artemisinin-containing therapies for malaria treatment are regularly co-Administered with ART. Currently, dolutegravir-based regimens are recommended as first-line therapy for HIV across most of Africa. Objectives: To …

Knowledge, use (misuse) and perceptions of over-the-counter analgesics in sub-Saharan Africa: a scoping review

BACKGROUND: Over-the-counter (OTC) analgesics are safe for pain-management when used as recommended. Misuse can increase the risk of hypertension and gastrointestinal problems. OBJECTIVE: To conduct a scoping review of the …

Women at high risk of HIV-infection in Kampala, Uganda, and their candidacy for PrEP

Pre-exposure prophylaxis (PrEP), antiretroviral medication for prevention of HIV-acquisition, is part of biomedical HIV prevention strategies recommended for people at risk of HIV-infection. A decision to take PrEP depends on …

"I prefer to take pills when I plan to have sex": Perceptions of on-demand versus daily oral pre-exposure prophylaxis among adolescents in Kampala, Uganda

There is limited information about the use of on-demand and daily pre-exposure prophylaxis (PrEP) among adolescents and young people (AYP) in sub-Saharan Africa. We explored perceptions of both regimens among …

Virologic Suppression in Nevirapine-Exposed HIV-Infected Infants Initiating Antiretroviral Therapy in Rural Uganda

We measured virologic suppression among 34 nevirapine (NVP)-exposed HIV-infected children with median age of 8.6 months (range: 3.2-19.9) initiating NVP-based antiretroviral therapy (ART) in rural Uganda. In Kaplan-Meier analysis, the …