Monthly sulfadoxine-pyrimethamine versus dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnancy: a double-blind, randomised, controlled, superiority trial

Background Intermittent treatment with sulfadoxine-pyrimethamine, recommended for prevention of malaria in pregnant women throughout sub-Saharan Africa, is threatened by parasite resistance. We assessed the efficacy and safety of intermittent preventive …

Monthly Sulfadoxine-Pyrimethamine Versus Dihydroartemisinin-Piperaquine for Intermittent Preventive Treatment of Malaria in Pregnancy: A Double-blind, Randomised, Controlled, Superiority Trial

Background Intermittent treatment with sulfadoxineâpyrimethamine, recommended for prevention of malaria inpregnant women throughout sub-Saharan Africa, is threatened by parasite resistance. We assessed the efficacy and safetyof intermittent preventive treatment with …

Assessment of an HIV-prevention intervention for couples in peri-urban Uganda: pervasive challenges to relationship quality also challenge intervention effectiveness

Reducing multiple and concurrent partnerships has been identified as a priority in generalised HIV epidemics, yet developing successful interventions to bring about such behaviour change has proven challenging. We offered …

COVID-19-Associated Guillain-Barre Syndrome: Atypical Para-infectious Profile, Symptom Overlap, and Increased Risk of Severe Neurological Complications

The concurrence of COVID-19 with Guillain-Barre syndrome (GBS) can increase the likelihood of neuromuscular respiratory failure, autonomic dysfunction, and other life-threatening symptoms. Currently, very little is known about the underlying …

Targeting wild-type Erythrocyte receptors for Plasmodium falciparum and vivax Merozoites by Zinc Finger Nucleases In- silico: Towards a Genetic Vaccine against Malaria

MEDLINE Abstract: UNLABELLED:<BR> <BR>BACKGROUND:<BR>Malaria causes immense human morbidity and mortality globally. The plasmodium species vivax and falciparum cause over 75 % clinical malaria cases. Until now, gene-based strategies against malaria …

Cohort Profile: The Iganga-Mayuge Health and Demographic Surveillance Site, Uganda (IMHDSS, Uganda)

âif It Does Not Endanger Me or the Health of My Baby, i Will Take It Up ...â Vaccine safety is an important consideration for maternal immunization acceptability in Rural Uganda: A qualitative study

Background: Maternal immunization is a successful and most costeffective public health strategy that protects pregnant women and their infants from vaccine-preventable diseases directly associated with reduced morbidity and mortality. Uganda …

Factors that predict fertility desires for people living with HIV infection at a support and treatment centre in Kabale, Uganda

Background: Studies from different contexts worldwide indicate that HIV positive patients manifest high-risk sexual behavior characterized by fertility intentions, multiple sexual partners, non-use of contraceptives and non-disclosure of HIV status …

Clinical versus laboratory screening for sexually transmitted infections prior to insertion of intrauterine contraception among women living with HIV/AIDS: a randomized controlled trial

STUDY QUESTION: Does laboratory testing after syndromic screening for sexually transmitted infections (STIs) reduce the rate of intrauterine contraception (IUC) removal among women living with HIV/AIDS (WLHA)?SUMMARY ANSWER: Additional laboratory …

Intrauterine Contraception Among Women Living With Human Immunodeficiency Virus A Randomized Controlled Trial

OBJECTIVE:To compare discontinuation rates of the levonorgestrel and copper intrauterine devices (IUDs) among women with human immunodeficiency virus.METHODS:A double-masked randomized trial was conducted at Mulago Hospital, Uganda. Women received either …