Experiences from East Africa and lessons in addressing the menstrual hygiene needs of women and girls

This practice paper outlines key results from research conducted by the International Federation of Red Cross and Red Crescent Societies (IFRC) in East Africa from 2012 to 2016. Implemented in …

Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial

Background Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD substrain vaccine. We …

A qualitative examination of secondary prophylaxis in rheumatic heart disease: Factors influencing adherence to secondary prophylaxis in Uganda

Background: Rheumatic heart disease (RHD) is the most common cause of heart disease amongUgandans age 15 to 49 years. Secondary prophylaxis with monthly injection of benzathine penicillin is effective in …

How equitable is social franchising? Case studies of three maternal healthcare franchises in Uganda and India

Substantial investments have been made in clinical social franchising to improve quality of care of private facilities in low-and middle-income countries but concerns have emerged that the benefits fail to …

Alcohol use and associated factors among adolescent boys and young men in Kampala, Uganda

Background Alcohol use leads to about 3 million deaths globally. The alcohol industry employs marketing strategies to establish their brands in the lives of young people at a time when …

Genome-wide transcriptional analyses in Anopheles mosquitoes reveal an unexpected association between salivary gland gene expression and insecticide resistance

Background: To combat malaria transmission, the Ugandan government has embarked upon an ambitious programme of indoor residual spraying (IRS) with a carbamate class insecticide, bendiocarb. In preparation for this campaign, …

The Protective Effect of Topical Rifamycin Treatment against Sternal Wound Infection in Diabetic Patients Undergoing on-Pump Coronary Artery Bypass Graft Surgery : Cardiovascular Topic

Objectives: The aim of this study was to investigate the protective effect of topical rifamycin SV treatment against sternal wound infection (SWI) in diabetic patients undergoing on-pump coronary artery bypass …

Quality assurance as an integral component of diagnostic testing in clinical laboratories and point-of-care testing: The Uganda experience

Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis

Background and Purpose- The PCSK9 (proprotein convertase subtilisin-kexin type 9) monoclonal antibody evolocumab lowered LDL (low-density lipoprotein) cholesterol by 59% to 0.8 (0.5-1.2) mmol/L and significantly reduced major vascular events …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …