2018 Annual report

Improved Viral Suppression With Streamlined Care in the SEARCH Study

Background: HIV differentiated service delivery (DSD) models are scaling up in resource-limited settings for stable patients; less is known about DSD outcomes for patients with viremia. We evaluated the effect …

Increasing incidence of pregnancy among women receiving HIV care and treatment at a large urban facility in western Uganda

Background: Antiretroviral treatment restores physical functioning and may have an impact on fertility desires. Counseling is given to HIV positive women to create awareness and to provide information on pregnancy …

Impact of CD8(+) T-cell activation on CD4(+) T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy

Objectives: To assess whether T-cell activation independently predicts the extent of CD4(+) T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy (ART).Design: Prospective cohort study.Methods: HIV-infected adults starting ART …

Factors associated with sexually transmitted infections among care-seeking adults in the African Cohort Study

Objectives Sexually transmitted infections (STIs) are a major cause of morbidity. Understanding drivers of transmission can inform effective prevention programs. We describe STI prevalence and identify factors associated with STIs …

Inhibitory Effect of Eco-Friendly Naturally Synthesized Silver Nanoparticles from the Leaf Extract of Medicinal Detarium microcarpum Plant on Pancreatic and Cervical Cancer Cells

BACKGROUND: Recently, nanoparticle synthesis by eco-friendly methods has received tremendous attention due to the method advantages and also because of the application of the nanoparticles in cancer research. Therefore, in …

The Impact of Adjuvant Chemoradiotherapy on the Overall Survival of Completely Resected Ampullary and Periampullary Carcinoma: An Updated Meta-Analysis

Purpose/Objective(s): Ampullary and Periampullary carcinomas (APAC) are uncommon gastrointestinal cancers that are often amenable to surgical resection. The benefit of postoperative adjuvant chemoradiotherapy (ACRT) in patients with completely resected localized …

Shaping the New Normal â The role of Adult Learning and Education in coping with the corona pandemic

The impact of equity factors on receipt of timely appropriate care for children with suspected malaria in eastern Uganda

Introduction Malaria accounts for more than one-tenth of sub-Saharan Africa's 2.8 million annual childhood deaths, and remains a leading cause of post-neonatal child mortality in Uganda. Despite increased community-based treatment …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …