Pan-ebolavirus protective therapy by two multifunctional human antibodies

Ebolaviruses cause a severe and often fatal illness with the potential for global spread. Monoclonal antibody based treatments that have become available recently have a narrow therapeutic spectrum and are …

Patterns of human herpesvirus-8 oral shedding among diverse cohorts of human herpesvirus-8 seropositive persons

Background: Human herpesvirus-8 (HHV-8), the etiologic agent of Kaposi sarcoma (KS), establishes lifelong latent infection with periodic lytic replication ("shedding") at mucosal sites, especially the oropharynx. Patterns of HHV-8 shedding …

"We have to clean ourselves to ensure that our children are healthy and beautiful": findings from a qualitative assessment of a hand hygiene poster in rural Uganda

BackgroundNeonatal sepsis is a major cause of mortality worldwide, with most deaths occurring in low-income countries. The World Health Organisation (WHO) 5 Moments for Hand Hygiene' poster has been used …

Ambulatory Blood Pressure Profiles in a Subset of HIV-Positive Patients Pre and Post Antiretroviral Therapy : Cardiovascular Topic

Corrigendum to: Characteristics of community savings groups in rural Eastern Uganda: opportunities for improving access to maternal health services (Global Health Action, (2017), 10, sup4, (1347363), 10.1080/16549716.2017.1347363)

Prevalence of Gastrointestinal Pathogens in Sub-Saharan Africa: Systematic Review and Meta-Analysis

A significant proportion of vulnerable people in sub-Saharan Africa (SSA) remain at risk for contracting diarrhoeal diseases due to the presence of many risk factors facilitating their transmission. A systematic …

EFFICACY OF âPRAGMACOM TRAININGâ IN SCHIZOPHRENIA: A RCT ON A NOVEL PRAGMATIC INTERVENTION...Schizophrenia International Research Society (SIRS) 2020 Congress

Background: A pragmatic disruption is observed in several clinical conditions and especially in schizophrenia. It is estimated that over 75% of patients affected by schizophrenia present a pervasive and wide …

Antigen-specific interferon-gamma responses and innate cytokine balance in TB-IRIS

MEDLINE Abstract: BACKGROUND: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) remains a poorly understood complication in HIV-TB patients receiving antiretroviral therapy (ART). TB-IRIS could be associated with an exaggerated immune response …

Infection control and treatment guidelines and neonatal mortality in a rural hospital in Uganda

Background: The neonatal mortality rate in Uganda has been 24-27/1000 live births for the last 14 years. Aim: To determine the impact on neonatal mortality of the introduction of infection …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …