Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis

Background: Cryptococcal meningitis is a leading cause of human immunodeficiency virus (HIV)- related death in sub-Saharan Africa. Whether a treatment regimen that includes a single high dose of liposomal amphotericin …

A Collaborative Family Planning Program in Rural Uganda Utilizing Community Health Workers

Background: Rural Ugandan women experience significant barriers to reproductive healthcare and family planning services, leading to a high unmet need for contraception. This community-based study investigates the barriers and assesses …

Cost-effectiveness of Preventive Therapy for Tuberculosis With Isoniazid and Rifapentine Versus Isoniazid Alone in High-Burden Settings

Background A short-course regimen of 3 months of weekly rifapentine and isoniazid (3HP) has recently been recommended by the World Health Organization as an alternative to at least 6 months …

Disability and poverty ­ reflections on research experiences in Africa and beyond

Background: Whilst broadly agreed in the literature that disability and poverty are closely interlinked, the empirical basis for this knowledge is relatively weak. Objectives: To describe and discuss the current …

Household food insecurity, maternal nutrition, environmental risks and infants' health outcomes: protocol of the IMPALA birth cohort study in Uganda

Introduction In low- and middle-income countries (LMICs), food insecurity and undernutrition disproportionately affect women of reproductive age, infants and young children. The disease burden from undernutrition in these vulnerable sections …

Paediatric admissions and outcome in a general intensive care unit

Background: It is believed that intensive care greatly improves the prognosis for critically ill children and that critically ill children admitted to a dedicated Paediatric Intensive Care Unit (PICU) do …

The impact of governance quality on mortality rates in Sub Saharan Africa

Background: The study examined the impact of governance quality on infant mortality, maternal mortality and adult female mortality in sub Saharan Africa.Data Source and Methods: World Bank data covering 2002 …

Ebola virus - from neglected threat to global emergency state

IN SEARCH OF THE RIGHT FORMULA: PUBLIC, PRIVATE AND COMMUNITY-DRIVEN PROVISION OF SAFE WATER IN RWANDA AND UGANDA

Over the last two decades, efforts have been made to find the right formula or formulae for delivering services to poor rural communities. Beginning in the late 1980s, decentralisation entailing …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …