Cerebral malaria is associated with long-term mental health disorders: A cross sectional survey of a long-term cohort

Background: Cerebral malaria (CM) and severe malarial anaemia (SMA) are associated with neuroâdevelopmentalimpairment in African children, but longâterm mental health disorders in these children are not well defined.Methods: A cohort …

A randomised non-inferiority trial with nested PK to assess DTG/3TC fixed dose formulations for the maintenance of virological suppression in children with HIV infection aged 2 to <15 years old

Exploring Institutional Research Ethics Systems: A Case Study From Uganda

BackgroundâThe increasing globalization of research drives a need for greater research ethicscapacity in low resource countries. Several programs have attempted to expand research ethicscapacity by training individuals, but few have …

Erratum: Prereferral rectal artesunate treatment by community-based treatment providers in ghana, guinea-bissau, tanzania, and uganda (study 18): A cluster-randomized trial(Clinical Infectious Diseases (2016) 63: 5(S312-21))

Experiences and views of healthcare professionals on the prescription of antibiotics in Eastern Uganda: A qualitative study

Objectives: This study aimed to explore the experiences and views of healthcare professionals on antibiotic prescription in Eastern Uganda. Methods: This was an exploratory qualitative study using semi-structured interviews. Participants …

A new highly sensitive enzyme-linked immunosorbent assay for the detection of Plasmodium falciparum histidine-rich protein 2 in whole blood

BackgroundThe detection of submicroscopic infections in low prevalence settings has become an increasingly important challenge for malaria elimination strategies. The current field rapid diagnostic tests (RDTs) for Plasmodium falciparum malaria …

Prevalence and factors associated with behavioural problems in children with epilepsy attending Mulago hospital, Uganda: A cross-sectional study

Purpose: : To determine the prevalence of behavioural problems and the associated factors in children with epilepsy (CWE).Methods: : This was a cross-sectional study conducted at Mulago National Referral Hospital, …

Accelerated malaria control towards its elimination in the African Region

Africa is the continent most affected by malaria; accounting for 86of the estimated 247 million malaria episodes and 91of malaria deaths worldwide in 2006. In high endemic countries in the …

The Role of Bone Marrow in SIV Pathogenesis Using the Rhesus Macaque Model

CD4+ memory T cells are depleted in mucosal tissues post human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection without restoration to pre-infection levels during progressive course of disease. …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …