Sensitive detection of HIV-1 resistance to Zidovudine and impact on treatment outcomes in low- to middle-income countries

Background: Thymidine analogs, namely AZT (Zidovudine or Retrovir (TM)) and d4T (Stavudine or Zerit (TM)) are antiretroviral drugs still employed in over 75% of first line combination antiretroviral therapy (cART) …

Correction: Long-Term Antiretroviral Treatment Adherence in HIV-Infected Adolescents and Adults in Uganda: A Qualitative Study

The Menstrual Practices Questionnaire (MPQ): development, elaboration, and implications for future research

High-quality evidence is needed to inform policies and programmes aiming to improve menstrual health. Quantitative studies must address the many evidence gaps in this field, and practitioners have increased monitoring …

Do the Clinical Management Guidelines for Covid-19 in African Countries Reflect the African Quality Palliative Care Standards? A Review of Current Guidelines

Context. Palliative care should be a component of COVID-19 management to relieve suffering, improve patient outcomes and save cost.Objectives. We aimed to identify and critically appraise the palliative care recommendations …

Spectrum of antibiotic resistance in UTI caused by Escherichia coli among HIV-infected patients in Uganda: a cross-sectional study

Background Antimicrobial drug resistance is one of the top ten threats to global health according to the World Health Organization. Urinary tract infections (UTIs) are among the most common bacterial …

What are the successful strategies for reducing malnutrition among young children in East Africa?

We analyzed the role that health programs played in improving the nutritional status of children aged five years and younger in East Africa during a period when health policies aiming …

Examining How to Strengthen the Primary Health Care Capacity for Early Breast Cancer Detection in Uganda: a Socioecological Approach

Breast cancer in Uganda is usually detected late as a result of complex and interacting factors. Although primary health care (PHC) is an integral platform for facilitating early detection of …

Hydroxyurea dose escalation for sickle cell Anemia in sub-Saharan Africa

BackgroundHydroxyurea has proven safety, feasibility, and efficacy in children with sickle cell anemia in sub-Saharan Africa, with studies showing a reduced incidence of vaso-occlusive events and reduced mortality. Dosing standards …

ACTION COALITION ON BODILY AUTONOMY & SEXUAL AND REPRODUCTIVE HEALTH AND RIGHTS

An Action Coalition on BodilyAutonomy and Sexual andReproductive Health and Rights(SRHR) was formed following theGeneration Equality Forum that washeld in Paris, France, in July 2021. Thisbuilds on the InternationalConference on …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …