Outcome measures to be considered on asthma in elderly

Purpose Of Review: Asthma is a chronic heterogeneous respiratory disease which is characterized by airflow limitation and variable respiratory symptoms. Asthma in patients more than 65 years of age has …

Anaphylaxis in Cold Induced Urticaria: A Case Report and Review of the Literature

Cold-induced urticaria is considered as a subtype of physical urticaria and also the second most common type of chronic inducible urticaria. Contact with cold surfaces or the environment may cause …

Using profile abbreviated version to guide pediatric hematology and oncology (Pho) opportunities prioritization and conversations in seven countries

Background and Aims: The Abbreviated Version of the Pediatric Oncology Facility Integrated Local Evaluation (PrOFILE) tool includes a subset of the questions and activities of the FullVersion. It aims to …

Phenotypic and genotypic analyses to guide selection of reverse transcriptase inhibitors in second-line HIV therapy following extended virological failure in Uganda

Hepcidin suppression by growth factors: Pathways and mechanisms

Systemic iron homeostasis requires management of iron distribution in the body as well as the size of total body iron stores. Both iron distribution in the body and the total …

Anti-phospholipid antibody levels as biomarker for monitoring tuberculosis treatment response

Standard methods to monitor tuberculosis (TB) treatment response rely on sputum microscopy and culture conversion. Alternatives to these methods are needed for those patients whose sputum tests are smear or …

Ethical Guidelines for Military-Based Health Research: an Unmet Need in Africa?

"Background: Achieving the highest standards of ethics in military health research is a challenging but crucial undertaking. The military environment is complex and African military health professionals struggle to maintain …

Viral and Clinical Oncology of Head and Neck Cancers

Purpose of ReviewThis study assesses the current state of knowledge of head and neck squamous cell carcinomas (HNSCC), which are malignancies arising from the orifices and adjacent mucosae of the …

HIV-Associated Gut Microbiome Differences and Immune Activation Are Dependent on Host Context

Even with antiretroviral therapy, individuals infected with Human Immunodeficiency Virus (HIV) experience greater mortality than uninfected individuals. This mortality is due in large part to inflammation-related non-communicable diseases, such as …

Antigen-specific interferon-gamma responses and innate cytokine balance in TB-IRIS

MEDLINE Abstract: BACKGROUND: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) remains a poorly understood complication in HIV-TB patients receiving antiretroviral therapy (ART). TB-IRIS could be associated with an exaggerated immune response …