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Current epidemiological profile of the Mpox virus in Africa; A Rapid Response Brief
ACRES
2024
brief
Health Research

BackgroundThe Mpox virus has caused two major outbreaks in the last three years. The first Mpox outbreak was in 2022,and it spread mainly in Europe and the Americas. The second …

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How to improve healthcare workersâ motivation to adopt and effectively utilize new technologies, such as smart paper technology, designed to improve data capture in their work environment; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: Over the past five years, Mukono district has implemented smart paper technology(SPT) to improve data capture and reporting efficiency in health facilities, focusing on the ExpandedProgram on Immunization (EPI). …

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Interventions to Improve HPV Screening Rates in Mukono District; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background:The Uganda Ministry of Health monitors HPV screening through district-level data collection,incentivizing active monitoring. In Mukono District, efforts have focused on educating HIV-infectedwomen and providing sample self-collection kits for convenience. …

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Strategies for reducing mortality due to motorcycle accidents; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: The rise in morbidity and mortality from motorcycle-related injuries is concerning, especially with the increasing popularity of motorcycles for transportation. Despite this trend, the management of crash victims has …

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Understanding the Problem of Maternal and Perinatal Deaths in Uganda; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: Maternal and perinatal mortality in Uganda remains a significant public health issue despite various healthcare interventions. Maternal mortality is defined as the death of a woman during pregnancy or …

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Why immunisation coverage is not recovering; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background:The Uganda Ministry of Health monitors HPV screening through district-level data collection, incentivizing active monitoring. In Mukono District, efforts have focused on educating HIV-infected women and providing sample self-collection kits …

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Why vaccine coverage, which dropped during the COVID-19 pandemic, is slow to recover, particularly in Kampala and Wakiso; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: The COVID-19 pandemic caused a major disruption to the delivery of healthcare services,including routine immunization, leading to a sharp decline in vaccine coverage. In 2021, 25 million childrenmissed their …

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Enhancing youthsâ role in the mitigation of climate change effects on Sexual and Reproductive Health; A Rapid Response Brief
ACRES
2023
brief
Health Research

Background: The impacts of climate change on sexual and reproductive health include increases in GBV, strained access to SRH services resulting in unwanted pregnancies, and sexually transmitted diseases,among others. Furthermore, …

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Strategies to improve vaccination data capture in Ugandaâs health information management system; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: In Mukono District, Uganda, the issue of zero-dose childrenâthose who have notreceived any routine vaccinationsâarises from discrepancies, for instance, in populationdenominator data, delayed reporting through the Health Management Information …

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References (4020)

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Health services strengthening in Africa - research is a key component S. Jaffar et al
Corrah Tumani, Mboup Souleymane, Jaffar Shabbar, Lazarus Jeffrey V., Onyebujoh Philip, Chakaya Jeremiah, Garrib Anupam, Mwaba Peter, Bellis Kevin, Egwaga Saidi and others...
2010
Journal, Article
Health Research

The author reflects on the importance of strengthening the health services in Africa. He states that performing research is the most important part of the strengthening process. The major challenge …

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Controlling diabetes and hypertension in sub-Saharan Africa: lessons from HIV programmes
Lazarus J.V., Mutungi G., Jaffar S., Ramaiya K., Karekezi C., Sewankambo N., Ruhweza Katahoire A., Kraef C., Musinguzi J., Birungi J. and others...
2021
Journal, Article
Health Research
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Childhood Tuberculosis and Malnutrition
Mupere Ezekiel, Jaganath Devan
2012
Journal, Article
Health Research

Despite the burden of both malnutrition and tuberculosis in children worldwide, there are few studies on the mechanisms that underlie this relationship. From available research, it appears that malnutrition is …

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A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda
Cattamanchi A, Andama A, Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M and others...
2021
Journal, Article
Health Research

Background. Xpert MTB/RIF Ultra (Xpert Ultra) has improved the sensitivity to detect pulmonary tuberculosis (TB) in adults. However, there have been limited prospective evaluations of its diagnostic accuracy in children.Methods. …

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Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda
Kakuru A, Kamya MR, Rosenthal PJ, Arinaitwe E, Greenhouse B, Dorsey G, Kaharuza F, Tappero J, Jagannathan P, Muhindo MK
2012
Journal, Article
Health Research

Background: The burden of malaria has decreased in parts of Africa following the scaling up of control interventions. However, similar data are limited from high transmission settings.Methods: A cohort of …

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IFNI|/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children
Kamya Moses R., Jagannathan Prasanna, Dorsey Grant, Eccles-James Ijeoma, Bowen Katherine, Nankya Felistas, Auma Ann, Wamala Samuel, Ebusu Charles, Muhindo Mary K. and others...
2014
Journal, Article
Health Research

MEDLINE Abstract: Although evidence suggests that T cells are critical for immunity to malaria, reliable T cell correlates of exposure to and protection from malaria among children living in endemic …

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Loss and dysfunction of V delta 2(+) gamma delta T cells are associated with clinical tolerance to malaria
Kamya MR, Tappero JW, Arinaitwe E, Greenhouse B, Dorsey G, Jagannathan P, Muhindo MK, Kim CC, Nankya F, Bowen K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The V delta 2(+) subset of gamma delta T cells …

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Loss and dysfunction of Vδ2+γδ T cells are associated with clinical tolerance to malaria
Arinaitwe E, Greenhouse B, Dorsey G, Kamya M R, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Kim C C, Muhindo M K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The Vδ2+ subset of γδ T cells have intrinsic reactivity …

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IFN gamma Responses to Pre-erythrocytic and Blood-stage Malaria Antigens Exhibit Differential Associations With Past Exposure and Subsequent Protection
Kamya MR, Dorsey G, Bigira V, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Feeney ME, Stoyanov C, Sikyomu E and others...
2015
Journal, Article
Health Research

Background. The malaria-specific T-cell response is believed to be important for protective immunity. Antimalarial chemoprevention may affect this response by altering exposure to malaria antigens.Methods.aEuro integral We performed interferon gamma …

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