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Current epidemiological profile of the Mpox virus in Africa; A Rapid Response Brief
ACRES
2024
brief
Health Research

BackgroundThe Mpox virus has caused two major outbreaks in the last three years. The first Mpox outbreak was in 2022,and it spread mainly in Europe and the Americas. The second …

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How to improve healthcare workersâ motivation to adopt and effectively utilize new technologies, such as smart paper technology, designed to improve data capture in their work environment; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: Over the past five years, Mukono district has implemented smart paper technology(SPT) to improve data capture and reporting efficiency in health facilities, focusing on the ExpandedProgram on Immunization (EPI). …

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Interventions to Improve HPV Screening Rates in Mukono District; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background:The Uganda Ministry of Health monitors HPV screening through district-level data collection,incentivizing active monitoring. In Mukono District, efforts have focused on educating HIV-infectedwomen and providing sample self-collection kits for convenience. …

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Strategies for reducing mortality due to motorcycle accidents; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: The rise in morbidity and mortality from motorcycle-related injuries is concerning, especially with the increasing popularity of motorcycles for transportation. Despite this trend, the management of crash victims has …

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Understanding the Problem of Maternal and Perinatal Deaths in Uganda; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: Maternal and perinatal mortality in Uganda remains a significant public health issue despite various healthcare interventions. Maternal mortality is defined as the death of a woman during pregnancy or …

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Why immunisation coverage is not recovering; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background:The Uganda Ministry of Health monitors HPV screening through district-level data collection, incentivizing active monitoring. In Mukono District, efforts have focused on educating HIV-infected women and providing sample self-collection kits …

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Why vaccine coverage, which dropped during the COVID-19 pandemic, is slow to recover, particularly in Kampala and Wakiso; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: The COVID-19 pandemic caused a major disruption to the delivery of healthcare services,including routine immunization, leading to a sharp decline in vaccine coverage. In 2021, 25 million childrenmissed their …

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Enhancing youthsâ role in the mitigation of climate change effects on Sexual and Reproductive Health; A Rapid Response Brief
ACRES
2023
brief
Health Research

Background: The impacts of climate change on sexual and reproductive health include increases in GBV, strained access to SRH services resulting in unwanted pregnancies, and sexually transmitted diseases,among others. Furthermore, …

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Strategies to improve vaccination data capture in Ugandaâs health information management system; A Rapid Response Brief
ACRES
2024
brief
Health Research

Background: In Mukono District, Uganda, the issue of zero-dose childrenâthose who have notreceived any routine vaccinationsâarises from discrepancies, for instance, in populationdenominator data, delayed reporting through the Health Management Information …

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References (4020)

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Feasibility of community at-home dried blood spot collection combined with pooled reverse transcription PCR as a viable and convenient method for malaria epidemiology studies
Balkus JE, Hergott DEB, Owalla TJ, Apio B, Lema J, Cemeri B, Akileng A, Seilie AM, Chavtur C, Staubus W and others...
2022
Journal, Article
Health Research

Background Many Plasmodium infections in endemic regions exist at densities below the limit of detection of standard diagnostic tools. These infections threaten control efforts and may impact vaccine and therapeutic …

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Earlier initiation of antiretroviral therapy, increased tuberculosis case finding and reduced mortality in a setting of improved HIV care: a retrospective cohort study
Kambugu A, Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA
2012
Journal, Article
Health Research

Objectives High early mortality after antiretroviral therapy (ART) initiation in resource-limited settings is associated with low baseline CD4 cell counts and a high burden of opportunistic infections. Our large urban …

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Integration of HIV and TB Services Results in Improved TB Treatment Outcomes and Earlier Prioritized ART Initiation in a Large Urban HIV Clinic in Uganda
Castelnuovo B, Manabe YC, Hermans SM, Hoepelman AIM, Lange JMA, Katabira C, Mbidde P, Coutinho A
2012
Journal, Article
Health Research

Background: The World Health Organization recommends that treatment of tuberculosis (TB) in HIV-infected patients should be integrated with HIV care. In December 2008, a separate outdoor-integrated TB/HIV clinic was instituted …

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Unrecognised tuberculosis at antiretroviral therapy initiation is associated with lower CD4+T cell recovery
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2012
Journal, Article
Health Research

Objectives To investigate whether an unrecognised diagnosis of tuberculosis (TB) at the start of antiretroviral therapy (ART) influences subsequent CD4+ T cell (CD4) count recovery in an urban HIV clinic …

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Risk of tuberculosis after antiretroviral treatment initiation: a comparison between efavirenz and nevirapine using inverse probability weighting
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2013
Journal, Article
Health Research

Background: There is a high incidence of tuberculosis (TB) early after antiretroviral therapy (ART) initiation. This historical cohort study evaluated the association of efavirenz (EFV) compared to nevirapine (NVP) with …

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Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert (TM) MTB/RIF era: a cohort study
Colebunders R, Castelnuovo B, Parkes-Ratanshi R, Manabe YC, Hermans SM, Babirye JA, Mbabazi O, Kakooza F, Sekaggya-Wiltshire C
2017
Journal, Article
Health Research

Background: The Xpert (TM) MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high …

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Development and Characterization of Broadly Cross-reactive Monoclonal Antibodies Against All Known Ebolavirus Species
Hernandez H., Marceau C., Halliday H., Callison J., Borisevich V., Escaffre O., Creech J., Feldmann H., Rockx B.
2015
Journal, Article
Health Research
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Effective strategies used to describe and address the burden of sickle cell disease in the Republic of Uganda: The Uganda Sickle Surveillance Study
Hernandez Arielle G.
2019
Dissertation
Health Research

Background:Sickle cell disease (SCD) contributes substantially to childhood mortality in sub-Saharan Africa. In the Republic of Uganda, the number of annual SCD births and the geographical distribution of the disease …

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Operational analysis of the national sickle cell screening programme in the Republic of Uganda
Hernandez Arielle G, Kiyaga Charles, Howard Thad A, Ssewanyana Isaac, Ndeezi Grace, Aceng Jane R, Ware Russell E
2021
Journal, Article
Health Research

Background: Sickle cell anaemia is a common global life-threatening haematological disorder. Most affected births occur in sub-Saharan Africa where children usually go undiagnosed and die early in life. Uganda's national …

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