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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Potential impacts of Genetic modification of mosquitoes in the control and prevention of malaria on individuals, community and ecology;A Rapid Response Brief
ACRES
2019
Rapid Review
Health Research

Background:Target Malaria is a not-for-profit research multi-national consortium in Africa and the United Kingdom that aims to develop and share technology for malaria control. In Uganda, the consortium partner is …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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Interventions to Improve HPV Screening Rates in Mukono District; A Rapid Response Brief
ACRES
2024
Rapid Review
Health Research

Background:The Uganda Ministry of Health monitors HPV screening through district-level data collection,incentivizing active monitoring. In Mukono District, efforts have focused on educating HIV-infectedwomen and providing sample self-collection kits for convenience. …

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How safe is the practice of Reflexology; A Rapid Response Brief
ACRES
2010
Rapid Review
Health Research

Background: Reflexology is a therapeutic method of relieving pain by stimulating predefined pressure points on the feet and hands. While its popularity has increased, the safety of reflexology has not …

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Should All Research Participants be Paid for Participation in Research;A Rapid Response Brief
ACRES
2019
Rapid Review
Health Research

Background:There is a split of opinion among the bioethicists and researchers on whether research participants need to be paid for participation in research. The payment is typically in terms of …

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Understanding the Problem of Maternal and Perinatal Deaths in Uganda; A Rapid Response Brief
ACRES
2024
Rapid Review
Health Research

Background: Maternal and perinatal mortality in Uganda remains a significant public health issue despite various healthcare interventions. Maternal mortality is defined as the death of a woman during pregnancy or …

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What are the policy options for re-centralization of the health sector in Uganda; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: Following World Bank and IMF-backed reforms in the 1990s, many low and middle-income countries decentralized their social sectors, including health. Despite some gains, a decline in services, especially for …

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What strategies can health systems in low-income settings employ for infection control; A Rapid Response Brief
ACRES
2012
Rapid Review
Health Research

Background: Healthcare-associated infections are a significant concern, even in settings with better healthcare practices. Factors such as inadequate equipment, staff shortages, and insufficient knowledge contribute to the suboptimal compliance with …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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References (4020)

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Health services strengthening in Africa - research is a key component S. Jaffar et al
Corrah Tumani, Mboup Souleymane, Jaffar Shabbar, Lazarus Jeffrey V., Onyebujoh Philip, Chakaya Jeremiah, Garrib Anupam, Mwaba Peter, Bellis Kevin, Egwaga Saidi and others...
2010
Journal, Article
Health Research

The author reflects on the importance of strengthening the health services in Africa. He states that performing research is the most important part of the strengthening process. The major challenge …

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Controlling diabetes and hypertension in sub-Saharan Africa: lessons from HIV programmes
Lazarus J.V., Mutungi G., Jaffar S., Ramaiya K., Karekezi C., Sewankambo N., Ruhweza Katahoire A., Kraef C., Musinguzi J., Birungi J. and others...
2021
Journal, Article
Health Research
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Childhood Tuberculosis and Malnutrition
Mupere Ezekiel, Jaganath Devan
2012
Journal, Article
Health Research

Despite the burden of both malnutrition and tuberculosis in children worldwide, there are few studies on the mechanisms that underlie this relationship. From available research, it appears that malnutrition is …

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A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda
Cattamanchi A, Andama A, Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M and others...
2021
Journal, Article
Health Research

Background. Xpert MTB/RIF Ultra (Xpert Ultra) has improved the sensitivity to detect pulmonary tuberculosis (TB) in adults. However, there have been limited prospective evaluations of its diagnostic accuracy in children.Methods. …

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Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda
Kakuru A, Kamya MR, Rosenthal PJ, Arinaitwe E, Greenhouse B, Dorsey G, Kaharuza F, Tappero J, Jagannathan P, Muhindo MK
2012
Journal, Article
Health Research

Background: The burden of malaria has decreased in parts of Africa following the scaling up of control interventions. However, similar data are limited from high transmission settings.Methods: A cohort of …

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IFNI|/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children
Kamya Moses R., Jagannathan Prasanna, Dorsey Grant, Eccles-James Ijeoma, Bowen Katherine, Nankya Felistas, Auma Ann, Wamala Samuel, Ebusu Charles, Muhindo Mary K. and others...
2014
Journal, Article
Health Research

MEDLINE Abstract: Although evidence suggests that T cells are critical for immunity to malaria, reliable T cell correlates of exposure to and protection from malaria among children living in endemic …

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Loss and dysfunction of V delta 2(+) gamma delta T cells are associated with clinical tolerance to malaria
Kamya MR, Tappero JW, Arinaitwe E, Greenhouse B, Dorsey G, Jagannathan P, Muhindo MK, Kim CC, Nankya F, Bowen K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The V delta 2(+) subset of gamma delta T cells …

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Loss and dysfunction of Vδ2+γδ T cells are associated with clinical tolerance to malaria
Arinaitwe E, Greenhouse B, Dorsey G, Kamya M R, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Kim C C, Muhindo M K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The Vδ2+ subset of γδ T cells have intrinsic reactivity …

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IFN gamma Responses to Pre-erythrocytic and Blood-stage Malaria Antigens Exhibit Differential Associations With Past Exposure and Subsequent Protection
Kamya MR, Dorsey G, Bigira V, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Feeney ME, Stoyanov C, Sikyomu E and others...
2015
Journal, Article
Health Research

Background. The malaria-specific T-cell response is believed to be important for protective immunity. Antimalarial chemoprevention may affect this response by altering exposure to malaria antigens.Methods.aEuro integral We performed interferon gamma …

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