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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Potential impacts of Genetic modification of mosquitoes in the control and prevention of malaria on individuals, community and ecology;A Rapid Response Brief
ACRES
2019
Rapid Review
Health Research

Background:Target Malaria is a not-for-profit research multi-national consortium in Africa and the United Kingdom that aims to develop and share technology for malaria control. In Uganda, the consortium partner is …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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Interventions to Improve HPV Screening Rates in Mukono District; A Rapid Response Brief
ACRES
2024
Rapid Review
Health Research

Background:The Uganda Ministry of Health monitors HPV screening through district-level data collection,incentivizing active monitoring. In Mukono District, efforts have focused on educating HIV-infectedwomen and providing sample self-collection kits for convenience. …

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How safe is the practice of Reflexology; A Rapid Response Brief
ACRES
2010
Rapid Review
Health Research

Background: Reflexology is a therapeutic method of relieving pain by stimulating predefined pressure points on the feet and hands. While its popularity has increased, the safety of reflexology has not …

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Should All Research Participants be Paid for Participation in Research;A Rapid Response Brief
ACRES
2019
Rapid Review
Health Research

Background:There is a split of opinion among the bioethicists and researchers on whether research participants need to be paid for participation in research. The payment is typically in terms of …

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Understanding the Problem of Maternal and Perinatal Deaths in Uganda; A Rapid Response Brief
ACRES
2024
Rapid Review
Health Research

Background: Maternal and perinatal mortality in Uganda remains a significant public health issue despite various healthcare interventions. Maternal mortality is defined as the death of a woman during pregnancy or …

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What are the policy options for re-centralization of the health sector in Uganda; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: Following World Bank and IMF-backed reforms in the 1990s, many low and middle-income countries decentralized their social sectors, including health. Despite some gains, a decline in services, especially for …

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What strategies can health systems in low-income settings employ for infection control; A Rapid Response Brief
ACRES
2012
Rapid Review
Health Research

Background: Healthcare-associated infections are a significant concern, even in settings with better healthcare practices. Factors such as inadequate equipment, staff shortages, and insufficient knowledge contribute to the suboptimal compliance with …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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References (4020)

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Feasibility of community at-home dried blood spot collection combined with pooled reverse transcription PCR as a viable and convenient method for malaria epidemiology studies
Balkus JE, Hergott DEB, Owalla TJ, Apio B, Lema J, Cemeri B, Akileng A, Seilie AM, Chavtur C, Staubus W and others...
2022
Journal, Article
Health Research

Background Many Plasmodium infections in endemic regions exist at densities below the limit of detection of standard diagnostic tools. These infections threaten control efforts and may impact vaccine and therapeutic …

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Earlier initiation of antiretroviral therapy, increased tuberculosis case finding and reduced mortality in a setting of improved HIV care: a retrospective cohort study
Kambugu A, Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA
2012
Journal, Article
Health Research

Objectives High early mortality after antiretroviral therapy (ART) initiation in resource-limited settings is associated with low baseline CD4 cell counts and a high burden of opportunistic infections. Our large urban …

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Integration of HIV and TB Services Results in Improved TB Treatment Outcomes and Earlier Prioritized ART Initiation in a Large Urban HIV Clinic in Uganda
Castelnuovo B, Manabe YC, Hermans SM, Hoepelman AIM, Lange JMA, Katabira C, Mbidde P, Coutinho A
2012
Journal, Article
Health Research

Background: The World Health Organization recommends that treatment of tuberculosis (TB) in HIV-infected patients should be integrated with HIV care. In December 2008, a separate outdoor-integrated TB/HIV clinic was instituted …

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Unrecognised tuberculosis at antiretroviral therapy initiation is associated with lower CD4+T cell recovery
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2012
Journal, Article
Health Research

Objectives To investigate whether an unrecognised diagnosis of tuberculosis (TB) at the start of antiretroviral therapy (ART) influences subsequent CD4+ T cell (CD4) count recovery in an urban HIV clinic …

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Risk of tuberculosis after antiretroviral treatment initiation: a comparison between efavirenz and nevirapine using inverse probability weighting
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2013
Journal, Article
Health Research

Background: There is a high incidence of tuberculosis (TB) early after antiretroviral therapy (ART) initiation. This historical cohort study evaluated the association of efavirenz (EFV) compared to nevirapine (NVP) with …

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Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert (TM) MTB/RIF era: a cohort study
Colebunders R, Castelnuovo B, Parkes-Ratanshi R, Manabe YC, Hermans SM, Babirye JA, Mbabazi O, Kakooza F, Sekaggya-Wiltshire C
2017
Journal, Article
Health Research

Background: The Xpert (TM) MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high …

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Development and Characterization of Broadly Cross-reactive Monoclonal Antibodies Against All Known Ebolavirus Species
Hernandez H., Marceau C., Halliday H., Callison J., Borisevich V., Escaffre O., Creech J., Feldmann H., Rockx B.
2015
Journal, Article
Health Research
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Effective strategies used to describe and address the burden of sickle cell disease in the Republic of Uganda: The Uganda Sickle Surveillance Study
Hernandez Arielle G.
2019
Dissertation
Health Research

Background:Sickle cell disease (SCD) contributes substantially to childhood mortality in sub-Saharan Africa. In the Republic of Uganda, the number of annual SCD births and the geographical distribution of the disease …

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Operational analysis of the national sickle cell screening programme in the Republic of Uganda
Hernandez Arielle G, Kiyaga Charles, Howard Thad A, Ssewanyana Isaac, Ndeezi Grace, Aceng Jane R, Ware Russell E
2021
Journal, Article
Health Research

Background: Sickle cell anaemia is a common global life-threatening haematological disorder. Most affected births occur in sub-Saharan Africa where children usually go undiagnosed and die early in life. Uganda's national …

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