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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Potential impacts of Genetic modification of mosquitoes in the control and prevention of malaria on individuals, community and ecology;A Rapid Response Brief
ACRES
2019
Rapid Review
Health Research

Background:Target Malaria is a not-for-profit research multi-national consortium in Africa and the United Kingdom that aims to develop and share technology for malaria control. In Uganda, the consortium partner is …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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Interventions to Improve HPV Screening Rates in Mukono District; A Rapid Response Brief
ACRES
2024
Rapid Review
Health Research

Background:The Uganda Ministry of Health monitors HPV screening through district-level data collection,incentivizing active monitoring. In Mukono District, efforts have focused on educating HIV-infectedwomen and providing sample self-collection kits for convenience. …

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How safe is the practice of Reflexology; A Rapid Response Brief
ACRES
2010
Rapid Review
Health Research

Background: Reflexology is a therapeutic method of relieving pain by stimulating predefined pressure points on the feet and hands. While its popularity has increased, the safety of reflexology has not …

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Should All Research Participants be Paid for Participation in Research;A Rapid Response Brief
ACRES
2019
Rapid Review
Health Research

Background:There is a split of opinion among the bioethicists and researchers on whether research participants need to be paid for participation in research. The payment is typically in terms of …

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Understanding the Problem of Maternal and Perinatal Deaths in Uganda; A Rapid Response Brief
ACRES
2024
Rapid Review
Health Research

Background: Maternal and perinatal mortality in Uganda remains a significant public health issue despite various healthcare interventions. Maternal mortality is defined as the death of a woman during pregnancy or …

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What are the policy options for re-centralization of the health sector in Uganda; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: Following World Bank and IMF-backed reforms in the 1990s, many low and middle-income countries decentralized their social sectors, including health. Despite some gains, a decline in services, especially for …

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What strategies can health systems in low-income settings employ for infection control; A Rapid Response Brief
ACRES
2012
Rapid Review
Health Research

Background: Healthcare-associated infections are a significant concern, even in settings with better healthcare practices. Factors such as inadequate equipment, staff shortages, and insufficient knowledge contribute to the suboptimal compliance with …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
Rapid Review
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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References (4020)

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Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective
JT Schwartze, M Havenga, WAM Bakker, AC Bradshaw, SA Nicklin
2022
Journal, Article
Health Research

Despite the development of novel pharmacological treatments, cardiovascular disease morbidity and mortality remain high indicating an unmet clinical need. Viral gene therapy enables targeted delivery of therapeutic transgenes and represents …

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Evaluating international research ethics capacity development: An empirical approach
Sewankambo Nelson K., Ali Joseph, Kass Nancy E., White Tara D., Hyder Adnan A.
2014
Journal, Article
Health Research

The US National Institutes of Health, Fogarty International Center (NIH-FIC) has, for the past 13 years, been a leading funder of international research ethics education for resource-limited settings. Nearly half …

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Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis
Giugliano Robert P., Pedersen Terje R., Saver Jeffrey L., Sever Peter S., Keech Anthony C., Bohula Erin A., Murphy Sabina A., Wasserman Scott M., Honarpour Narimon, Wang Huei and others...
2020
Journal, Article
Health Research

Background and Purpose- The PCSK9 (proprotein convertase subtilisin-kexin type 9) monoclonal antibody evolocumab lowered LDL (low-density lipoprotein) cholesterol by 59% to 0.8 (0.5-1.2) mmol/L and significantly reduced major vascular events …

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The accuracy of the patient health questionnaire-9 algorithm for screening to detect major depression: An individual participant data meta-analysis
Patel Vikram, He Chen, Levis Brooke, Riehm Kira E., Saadat Nazanin, Levis Alexander W., Azar Marleine, Rice Danielle B., Krishnan Ankur, Wu Yin and others...
2020
Journal, Article
Health Research

Background: Screening for major depression with the Patient Health Questionnaire-9 (PHQ-9) can be done using a cutoff or the PHQ-9 diagnostic algorithm. Many primary studies publish results for only one …

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Global Programme Report 2019
ERIKS
Generic
Health Research
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Reduced virus replication, proinflammatory cytokine production, and delayed macrophage cell death in human PBMCs infected with the newly discovered Bundibugyo ebolavirus relative to Zaire ebolavirus
Rollin PE, Metcalfe MG, Gupta M, Goldsmith CS, Spipopoulou CF
2010
Journal, Article
Health Research

Bundibugyo ebolavirus is a newly identified Ebolavirus species. The virus was responsible for a recent hemorrhagic fever outbreak in Uganda with an approximate 30% case fatality rate. In this study, …

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P261âFollow-up assessment of participants with urethral discharge syndrome in Kampala, Uganda: Lessons learned for future STI control Interventions
Kiragga A, Parkes-Ratanshi R, Aketoko A Onzia, Hamill M, Manabe Y, Gaydos C, Melendez J, Nakku-Joloba E, Zawedde A, Kyambadde P
2021
Journal, Article
Health Research

BackgroundAfter effective treatment, persons diagnosed with a sexually transmitted infections (STI) are encouraged to modify behavior and notify partners. In resource-limited settings (RLS), follow-up assessment is limited by a variety …

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Mixed-method study to assess the feasibility, acceptability and early effectiveness of the Hospital to Home programme for follow-up of high-risk newborns in a rural district of Central Uganda: a study protocol
Waiswa P, Otai C, Nyonyintono J, Kabugo D, Nakamura H, Magnusson B, Vaughan M, Niyonshaba B, Nakiganda C, Haddix-McKay K and others...
2021
Journal, Article
Health Research

Introduction A follow-up programme designed for high-risk newborns discharged from inpatient newborn units in low-resource settings is imperative to ensure these newborns receive the healthiest possible start to life. We …

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Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda
Amanyire G, Kwarisiima D, Kabami J, Chamie G, Jain V, Black D, Kamya M R, Clark T D, Charlebois E D, Havlir D V and others...
2014
Journal, Article
Health Research

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …

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