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What are the effects of clinical pathways in cancer management; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:Disease or diagnosis (Cancer) management pathways may be divided into patient pathways and clinical pathways. A clinical pathway is a documented sequence of clinical interventions assisting a patient with a …

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What are the health effects (benefits and risks) of steam baths (Saunas); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Steam bathing, practiced globally and increasingly in Uganda, involves exposure to heat in a confined space. Despite its popularity, the health effects of steam bathing remain a concern for …

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What strategies can health systems in low-income settings employ for infection control; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Healthcare-associated infections are a significant concern, even in settings with better healthcare practices. Factors such as inadequate equipment, staff shortages, and insufficient knowledge contribute to the suboptimal compliance with …

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What are the key implementation considerations for the national immunization policy; A Rapid Response Brief
ACRES
2013
brief
Health Research

Background: Immunization is a critical public health intervention, significantly reducing the burden of infectious diseases. Effective implementation of immunization policies is essential to achieve desired health outcomes, including herd immunity.Rapid …

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Feasibility and Effects of task sharing and mhealth by VHTS in the prevention and control of hypertension and Diabetes Mellitus;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Village Health Teams (VHTs) or Lay health workers have been shown to a play an important role of increasing access to healthcare within communities and homes for infectious diseases such …

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Potential impacts of Genetic modification of mosquitoes in the control and prevention of malaria on individuals, community and ecology;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Target Malaria is a not-for-profit research multi-national consortium in Africa and the United Kingdom that aims to develop and share technology for malaria control. In Uganda, the consortium partner is …

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Should All Research Participants be Paid for Participation in Research;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:There is a split of opinion among the bioethicists and researchers on whether research participants need to be paid for participation in research. The payment is typically in terms of …

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Strategies to improve the coverage of at least four antenatal care visits in Mukono district;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Attending more antenatal visits is associated with better maternal and neonatal outcomes, and skilled birth attendant at delivery. However, the Uganda demographic health survey 2016 estimates that 97% have attended …

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Considerations for re-opening academic institutions in Uganda amidst the COVID-19 pandemic; A Rapid Response Brief
ACRES
2020
brief
Health Research

BackgroundSchool closure was one of the many measures implemented by the government of Uganda in her response to enforce social distancing and control the COVID-19 pandemic. However with the prolonged …

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Covid-19 control: How can an LMIC implement a jurisdictional lockdown to prevent spread of infection in the community; A Rapid Response Brief
ACRES
2020
brief
Health Research

Background: The WHO declared Covid-19 a pandemic. At this stage in many countries, one of the questions yet to be answered with certainty is where a good proportion of people …

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References (4020)

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Health services strengthening in Africa - research is a key component S. Jaffar et al
Corrah Tumani, Mboup Souleymane, Jaffar Shabbar, Lazarus Jeffrey V., Onyebujoh Philip, Chakaya Jeremiah, Garrib Anupam, Mwaba Peter, Bellis Kevin, Egwaga Saidi and others...
2010
Journal, Article
Health Research

The author reflects on the importance of strengthening the health services in Africa. He states that performing research is the most important part of the strengthening process. The major challenge …

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Controlling diabetes and hypertension in sub-Saharan Africa: lessons from HIV programmes
Lazarus J.V., Mutungi G., Jaffar S., Ramaiya K., Karekezi C., Sewankambo N., Ruhweza Katahoire A., Kraef C., Musinguzi J., Birungi J. and others...
2021
Journal, Article
Health Research
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Childhood Tuberculosis and Malnutrition
Mupere Ezekiel, Jaganath Devan
2012
Journal, Article
Health Research

Despite the burden of both malnutrition and tuberculosis in children worldwide, there are few studies on the mechanisms that underlie this relationship. From available research, it appears that malnutrition is …

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A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda
Cattamanchi A, Andama A, Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M and others...
2021
Journal, Article
Health Research

Background. Xpert MTB/RIF Ultra (Xpert Ultra) has improved the sensitivity to detect pulmonary tuberculosis (TB) in adults. However, there have been limited prospective evaluations of its diagnostic accuracy in children.Methods. …

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Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda
Kakuru A, Kamya MR, Rosenthal PJ, Arinaitwe E, Greenhouse B, Dorsey G, Kaharuza F, Tappero J, Jagannathan P, Muhindo MK
2012
Journal, Article
Health Research

Background: The burden of malaria has decreased in parts of Africa following the scaling up of control interventions. However, similar data are limited from high transmission settings.Methods: A cohort of …

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IFNI|/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children
Kamya Moses R., Jagannathan Prasanna, Dorsey Grant, Eccles-James Ijeoma, Bowen Katherine, Nankya Felistas, Auma Ann, Wamala Samuel, Ebusu Charles, Muhindo Mary K. and others...
2014
Journal, Article
Health Research

MEDLINE Abstract: Although evidence suggests that T cells are critical for immunity to malaria, reliable T cell correlates of exposure to and protection from malaria among children living in endemic …

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Loss and dysfunction of V delta 2(+) gamma delta T cells are associated with clinical tolerance to malaria
Kamya MR, Tappero JW, Arinaitwe E, Greenhouse B, Dorsey G, Jagannathan P, Muhindo MK, Kim CC, Nankya F, Bowen K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The V delta 2(+) subset of gamma delta T cells …

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Loss and dysfunction of Vδ2+γδ T cells are associated with clinical tolerance to malaria
Arinaitwe E, Greenhouse B, Dorsey G, Kamya M R, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Kim C C, Muhindo M K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The Vδ2+ subset of γδ T cells have intrinsic reactivity …

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IFN gamma Responses to Pre-erythrocytic and Blood-stage Malaria Antigens Exhibit Differential Associations With Past Exposure and Subsequent Protection
Kamya MR, Dorsey G, Bigira V, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Feeney ME, Stoyanov C, Sikyomu E and others...
2015
Journal, Article
Health Research

Background. The malaria-specific T-cell response is believed to be important for protective immunity. Antimalarial chemoprevention may affect this response by altering exposure to malaria antigens.Methods.aEuro integral We performed interferon gamma …

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