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What are the effects of clinical pathways in cancer management; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:Disease or diagnosis (Cancer) management pathways may be divided into patient pathways and clinical pathways. A clinical pathway is a documented sequence of clinical interventions assisting a patient with a …

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What are the health effects (benefits and risks) of steam baths (Saunas); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Steam bathing, practiced globally and increasingly in Uganda, involves exposure to heat in a confined space. Despite its popularity, the health effects of steam bathing remain a concern for …

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What strategies can health systems in low-income settings employ for infection control; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Healthcare-associated infections are a significant concern, even in settings with better healthcare practices. Factors such as inadequate equipment, staff shortages, and insufficient knowledge contribute to the suboptimal compliance with …

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What are the key implementation considerations for the national immunization policy; A Rapid Response Brief
ACRES
2013
brief
Health Research

Background: Immunization is a critical public health intervention, significantly reducing the burden of infectious diseases. Effective implementation of immunization policies is essential to achieve desired health outcomes, including herd immunity.Rapid …

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Feasibility and Effects of task sharing and mhealth by VHTS in the prevention and control of hypertension and Diabetes Mellitus;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Village Health Teams (VHTs) or Lay health workers have been shown to a play an important role of increasing access to healthcare within communities and homes for infectious diseases such …

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Potential impacts of Genetic modification of mosquitoes in the control and prevention of malaria on individuals, community and ecology;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Target Malaria is a not-for-profit research multi-national consortium in Africa and the United Kingdom that aims to develop and share technology for malaria control. In Uganda, the consortium partner is …

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Should All Research Participants be Paid for Participation in Research;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:There is a split of opinion among the bioethicists and researchers on whether research participants need to be paid for participation in research. The payment is typically in terms of …

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Strategies to improve the coverage of at least four antenatal care visits in Mukono district;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Attending more antenatal visits is associated with better maternal and neonatal outcomes, and skilled birth attendant at delivery. However, the Uganda demographic health survey 2016 estimates that 97% have attended …

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Considerations for re-opening academic institutions in Uganda amidst the COVID-19 pandemic; A Rapid Response Brief
ACRES
2020
brief
Health Research

BackgroundSchool closure was one of the many measures implemented by the government of Uganda in her response to enforce social distancing and control the COVID-19 pandemic. However with the prolonged …

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Covid-19 control: How can an LMIC implement a jurisdictional lockdown to prevent spread of infection in the community; A Rapid Response Brief
ACRES
2020
brief
Health Research

Background: The WHO declared Covid-19 a pandemic. At this stage in many countries, one of the questions yet to be answered with certainty is where a good proportion of people …

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References (4020)

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P-A12âAssessing quality of HIV treatment in the United States Military HIV Research Program/President's Emergency Plan for AIDS Relief (PEPFAR)-supported programs in Africa
Hughes Lindsay, Hamm Tiffany, Crawford Keith, Lenneman Tessa, Kibuuka Hannah, Maswai Jonah, Clinkscales Jessica, Robb Merlin, Michael Nelson
2014
Journal, Article
Health Research

Following rapid scale up of ART, attention is now focused on improving quality of care and identifying populations and interventions to maximize impact and long-term effectiveness. Viral load, considered the …

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Impact of Exposure to Long Lasting Insecticide Treated Nets on Mosquito Survival and Behaviour at the Net Interface in Insecticide Susceptible and Resistant Strains of the Afrotropical Anopheles Mosquito
Hughes Angela Jane
2018
Dissertation
Health Research

The central role of long-lasting insecticidal nets (LLINs) in malaria prevention in Africa is threatened by insecticide resistance. Little is known about mosquito behaviour near, or of the importance of …

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Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women
Hughes E, Mwebaza N, Huang LS, Kajubi R, Nguyen V, Nyunt MM, Orukan F, Mwima MW, Parikh S, Aweeka F
2020
Journal, Article
Health Research

Background: The choice of malaria treatment for HIV-infected pregnant women receiving efavirenz-based antiretroviral therapy must consider the potential impact of drug interactions on antimalarial exposure and clinical response. The aim …

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Piperaquine Exposure Is Altered by Pregnancy, HIV, and Nutritional Status in Ugandan Women
Zhang N, Kakuru A, Havlir D, Kamya M, Natureeba P, Dorsey G, Rosenthal P J, Huang L, Muhindo M, Hughes E and others...
2020
Journal, Article
Health Research

Dihydroartemisinin-piperaquine (DHA-PQ) provides highly effective therapy and chemoprevention for malaria in pregnant African women. PQ concentrations of >10.3âng/ml have been associated with reduced maternal parasitemia, placental malaria, and improved birth …

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Neurosurgical Decision-Making and Ethical Considerations in the Treatment of Traumatic Brain Injury
Hughes Jasmine
2022
Dissertation
Health Research

Globally, disparities in the availability of surgical care are prevalent, and for specialty care such as neurosurgery, services are typically scarce to non-existent. In low-and-middle-income countries, most medical centers have …

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Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women
Dorsey G., Rosenthal P.J., Hughes E., Wallender E., Kajubi R., Jagannathan P., Ochieng T., Kakuru A., Kamya M.R., Clark T.D. and others...
2022
Journal, Article
Health Research

BACKGROUND: Intermittent preventive treatment with monthly dihydroartemisinin-piperaquine (DHA-PQ) is highly effective at preventing both malaria during pregnancy and placental malaria. Piperaquine prolongs the corrected QT interval (QTc), and it is …

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Long-Term virological outcomes, failure and acquired resistance in a large cohort of Ugandan children
Kityo C, Mugyenyi P, Huibers M H.W, Boerma R S, Kaudha E, Sigaloff K C.E, Balinda S N, Bertagnolio S, Nakanjako R, Calis J C.J and others...
2019
Journal, Article
Health Research

Objectives: To evaluate long-term virological failure (VF) and drug resistance among HIV-infected Ugandan chil-dren on first-line ART.Methods: In a multicentre prospective cohort study, viral load (VL) and drug resistance mutations …

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PRECISION PUBLIC HEALTH AND PANDEMIC PREPAREDNESS: QUANTIFYING TRAVEL TIME TO HEALTH CARE AND LOCATIONS AT RISK FOR PATHOGEN TRANSMISSION
et al, Hulland E., Wiens K., Shirude S., Bell B., Rabinowitz P., Institute for Health Metrics, Evaluation Seattle W. A. United States
2019
Journal, Article
Health Research

AFRICAN DEVELOPMENT Abstract: Infectious disease threats exist even in places without evidence of past events, and without clear preparedness plans to prevent, detect, and respond to such threats, outbreaks can …

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Mechanisms of paediatric trauma at a rural hospital in Uganda.
Hulme P.
2010
Journal, Article
Health Research
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Mechanisms of trauma at a rural hospital in Uganda
Hulme P.
2010
Journal, Article
Health Research
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