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What are the effects of clinical pathways in cancer management; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:Disease or diagnosis (Cancer) management pathways may be divided into patient pathways and clinical pathways. A clinical pathway is a documented sequence of clinical interventions assisting a patient with a …

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What are the health effects (benefits and risks) of steam baths (Saunas); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Steam bathing, practiced globally and increasingly in Uganda, involves exposure to heat in a confined space. Despite its popularity, the health effects of steam bathing remain a concern for …

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What strategies can health systems in low-income settings employ for infection control; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Healthcare-associated infections are a significant concern, even in settings with better healthcare practices. Factors such as inadequate equipment, staff shortages, and insufficient knowledge contribute to the suboptimal compliance with …

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What are the key implementation considerations for the national immunization policy; A Rapid Response Brief
ACRES
2013
brief
Health Research

Background: Immunization is a critical public health intervention, significantly reducing the burden of infectious diseases. Effective implementation of immunization policies is essential to achieve desired health outcomes, including herd immunity.Rapid …

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Feasibility and Effects of task sharing and mhealth by VHTS in the prevention and control of hypertension and Diabetes Mellitus;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Village Health Teams (VHTs) or Lay health workers have been shown to a play an important role of increasing access to healthcare within communities and homes for infectious diseases such …

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Potential impacts of Genetic modification of mosquitoes in the control and prevention of malaria on individuals, community and ecology;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Target Malaria is a not-for-profit research multi-national consortium in Africa and the United Kingdom that aims to develop and share technology for malaria control. In Uganda, the consortium partner is …

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Should All Research Participants be Paid for Participation in Research;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:There is a split of opinion among the bioethicists and researchers on whether research participants need to be paid for participation in research. The payment is typically in terms of …

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Strategies to improve the coverage of at least four antenatal care visits in Mukono district;A Rapid Response Brief
ACRES
2019
brief
Health Research

Background:Attending more antenatal visits is associated with better maternal and neonatal outcomes, and skilled birth attendant at delivery. However, the Uganda demographic health survey 2016 estimates that 97% have attended …

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Considerations for re-opening academic institutions in Uganda amidst the COVID-19 pandemic; A Rapid Response Brief
ACRES
2020
brief
Health Research

BackgroundSchool closure was one of the many measures implemented by the government of Uganda in her response to enforce social distancing and control the COVID-19 pandemic. However with the prolonged …

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Covid-19 control: How can an LMIC implement a jurisdictional lockdown to prevent spread of infection in the community; A Rapid Response Brief
ACRES
2020
brief
Health Research

Background: The WHO declared Covid-19 a pandemic. At this stage in many countries, one of the questions yet to be answered with certainty is where a good proportion of people …

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References (4020)

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Feasibility of community at-home dried blood spot collection combined with pooled reverse transcription PCR as a viable and convenient method for malaria epidemiology studies
Balkus JE, Hergott DEB, Owalla TJ, Apio B, Lema J, Cemeri B, Akileng A, Seilie AM, Chavtur C, Staubus W and others...
2022
Journal, Article
Health Research

Background Many Plasmodium infections in endemic regions exist at densities below the limit of detection of standard diagnostic tools. These infections threaten control efforts and may impact vaccine and therapeutic …

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Earlier initiation of antiretroviral therapy, increased tuberculosis case finding and reduced mortality in a setting of improved HIV care: a retrospective cohort study
Kambugu A, Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA
2012
Journal, Article
Health Research

Objectives High early mortality after antiretroviral therapy (ART) initiation in resource-limited settings is associated with low baseline CD4 cell counts and a high burden of opportunistic infections. Our large urban …

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Integration of HIV and TB Services Results in Improved TB Treatment Outcomes and Earlier Prioritized ART Initiation in a Large Urban HIV Clinic in Uganda
Castelnuovo B, Manabe YC, Hermans SM, Hoepelman AIM, Lange JMA, Katabira C, Mbidde P, Coutinho A
2012
Journal, Article
Health Research

Background: The World Health Organization recommends that treatment of tuberculosis (TB) in HIV-infected patients should be integrated with HIV care. In December 2008, a separate outdoor-integrated TB/HIV clinic was instituted …

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Unrecognised tuberculosis at antiretroviral therapy initiation is associated with lower CD4+T cell recovery
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2012
Journal, Article
Health Research

Objectives To investigate whether an unrecognised diagnosis of tuberculosis (TB) at the start of antiretroviral therapy (ART) influences subsequent CD4+ T cell (CD4) count recovery in an urban HIV clinic …

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Risk of tuberculosis after antiretroviral treatment initiation: a comparison between efavirenz and nevirapine using inverse probability weighting
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2013
Journal, Article
Health Research

Background: There is a high incidence of tuberculosis (TB) early after antiretroviral therapy (ART) initiation. This historical cohort study evaluated the association of efavirenz (EFV) compared to nevirapine (NVP) with …

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Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert (TM) MTB/RIF era: a cohort study
Colebunders R, Castelnuovo B, Parkes-Ratanshi R, Manabe YC, Hermans SM, Babirye JA, Mbabazi O, Kakooza F, Sekaggya-Wiltshire C
2017
Journal, Article
Health Research

Background: The Xpert (TM) MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high …

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Development and Characterization of Broadly Cross-reactive Monoclonal Antibodies Against All Known Ebolavirus Species
Hernandez H., Marceau C., Halliday H., Callison J., Borisevich V., Escaffre O., Creech J., Feldmann H., Rockx B.
2015
Journal, Article
Health Research
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Effective strategies used to describe and address the burden of sickle cell disease in the Republic of Uganda: The Uganda Sickle Surveillance Study
Hernandez Arielle G.
2019
Dissertation
Health Research

Background:Sickle cell disease (SCD) contributes substantially to childhood mortality in sub-Saharan Africa. In the Republic of Uganda, the number of annual SCD births and the geographical distribution of the disease …

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Operational analysis of the national sickle cell screening programme in the Republic of Uganda
Hernandez Arielle G, Kiyaga Charles, Howard Thad A, Ssewanyana Isaac, Ndeezi Grace, Aceng Jane R, Ware Russell E
2021
Journal, Article
Health Research

Background: Sickle cell anaemia is a common global life-threatening haematological disorder. Most affected births occur in sub-Saharan Africa where children usually go undiagnosed and die early in life. Uganda's national …

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