Virological remission after antiretroviral therapy interruption in female African HIV seroconverters

Virological remission after antiretroviral therapyinterruption in female African HIV seroconvertersMorgane Gosseza, Genevieve Elizabeth Martina, Matthew Pacea,Gita Ramjeeb, Anamika Premrajb, Pontiano Kaleebuc, Helen Reesd,Jamie Inshawe , Wolfgang Stâ¬ohr e, Jodi Meyerowitza, …

The One Nutrition in Complex Environments (ONCE) study protocol a cluster-randomized multi-level multi-sectoral intervention to improve nutrition in Uganda

Objective: To implement and measure the effects of a multi-level multi-sectoral social behavior change (SBC) intervention in Agago District of Northern Uganda and to determine the potential for scale-up.Intervention: Compare …

Evaluation of Mechanisms to Improve Performance of Mobile Phone Surveys in Low- and Middle-Income Countries: Research Protocol

Background: Mobile phone ownership and access have increased rapidly across low- and middle-income countries (LMICs) within the last decade. Concomitantly, LMICs are experiencing demographic and epidemiologic transitions, where non-communicable diseases …

Long-term observation of absence of REM sleep caused by pontine cavernous hemangioma

HIV-Associated Gut Microbiome Differences and Immune Activation Are Dependent on Host Context

Even with antiretroviral therapy, individuals infected with Human Immunodeficiency Virus (HIV) experience greater mortality than uninfected individuals. This mortality is due in large part to inflammation-related non-communicable diseases, such as …

Changing HIV treatment eligibility under health system constraints in sub-Saharan Africa: investment needs, population health gains, and cost-effectiveness

Objective: We estimated the investment needs, population health gains, and cost-effectiveness of different policy options for scaling-up prevention and treatment of HIV in the 10 countries that currently comprise 80% …

Considering the cultural context in psychopathology formulations

Background. Mental health research appears to be continually transforming. Recent literature reflects a greater appreciation for the ways in which pathoplastic features of culture modulate emotional regulation. This article introduces …

Lower Pre-Treatment T Cell Activation in Early- and Late-Onset Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome

BackgroundTuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is aninflammatory complication in HIV-TB co-infected patients receiving antiretroviral therapy(ART). The role of disturbed T cell reconstitution in TB-IRIS is not well understood. Weinvestigated …

S U P P O R T I N G U G A N D A S R U R A L P R I M A R Y S C H O O L S D U R I N G T H E C O V I D - 1 9 S H U T D O W N F I N D I N G S F R OM A S U R V E Y O F H E A D T E A C H E R S I N MU K O N O D I S T R I C T , U G A N D A

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …