Stroke Prevention With the PCSK9 (Proprotein Convertase Subtilisin-Kexin Type 9) Inhibitor Evolocumab Added to Statin in High-Risk Patients With Stable Atherosclerosis

Background and Purpose- The PCSK9 (proprotein convertase subtilisin-kexin type 9) monoclonal antibody evolocumab lowered LDL (low-density lipoprotein) cholesterol by 59% to 0.8 (0.5-1.2) mmol/L and significantly reduced major vascular events …

Access to pediatric surgery delivered by general surgeons and anesthesia providers in Uganda: Results from 2 rural regional hospitals

Background: Signiï¬cant limitations in pediatric surgical capacity exist in low- and middle-incomecountries, especially in rural regions. Recent global childrenâs surgical guidelines suggest training andsupport of general surgeons in rural regional …

Bibliometric analysis of sub-Saharan African and US authorship in publications about sub-Saharan Africa funded by the Fogarty International Center, 2008â2020

BackgroundAuthorship and author order have been used as one measure to characterise equity in research partnerships. First and last (senior) authorships often denote scientific merit as well as potential for …

Fruit and vegetable intake and mental health among family caregivers of people with dementia in Uganda

Prevalence and risk factors for third- and fourth-degree perineal lacerations during vaginal delivery: a multi-country study

Objective To investigate the prevalence and risk factors of third- and fourth-degree perineal lacerations in 24, mainly developing, countries.Design Analysis using cross-sectional data from the WHO Global Survey on Maternal …

Thrombocytopenia may mediate disease severity in plasmodium falciparum malaria through reduced transforming growth factor beta-1 regulation of proinflammatory and anti-inflammatory cytokines

Background: Transforming growth factor beta-1 (TGF-β1) is an important regulator of inflammation. Platelets are a major source of TGF-β1 and are reduced in severe malaria. However, the relationships between TGF-β1 …

Multi-Center, Randomized, Efficacy Study of COVID-19 MRNa Vaccine in Regions with SARS-CoV-2 Variants of Concernâ in Uganda

Differences in Maternal Behaviors Affecting Child Health Status in Probably Depressed and Non-Depressed Mothers in Rural Uganda

Postpartum depression (PPD) is a common perinatal mental health disorder (CPMD) extensively linked to poor child health outcomes, including increased risk of illness, stunting and underweight. Rates of PPD and …

Evaluating the systems used to monitor HIV populations accessing therapy and care in low-income and lower-middle-income countries

Objectives: The scale-up of delivery of antiretroviral therapy (ART) in low-income andmiddle-income countries has been coupled with the collection of data aimed atmonitoring the welfare of the HIV-positive and treated …

Successful antiretroviral therapy delivery and retention in care among asymptomatic individuals with high CD4+T-cell counts above 350 cells/ml in rural Uganda

Background: HIV antiretroviral therapy (ART) is being rapidly scaled up in sub-Saharan Africa, including recently patients with CD4+ T-cell counts above 350 cells/μl. However, concerns persist about adherence and virologic …