Digital Evidence Base Logo
Filters
SDGs
Priority Areas
Research Outcomes
Document Type
Year
What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

View Details
What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

View Details
What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

View Details
What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

View Details
What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

View Details
What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

View Details
What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

View Details
What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

View Details
Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

View Details
What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

View Details

References (4020)

Show:
HIV-Related Stigma Among Youth Living With HIV in Western Uganda
Vindevogel S, Kimera E, Rubaihayo J, Reynaert D, De Maeyer J, Engelen AM, Bilsen J, Kintu MJ
2021
Journal, Article
Health Research

We present an explanatory theory for HIV-related stigma from the perspectives of youth living with HIV/AIDS (YLWHA) in Western Uganda, on which the fight against this relentless stigma in this …

View Details
Integrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control
Mutungi G., Ssinabulya I., Neupane D., Schwartz J.I., Semitala F.C., Kimera I.D., Namugenyi C., Musimbaggo D.J., Ssenyonjo R., Atukunda P. and others...
2022
Journal, Article
Health Research

Multi-month dispensing (MMD) is a patient-centered approach in which stable patients receive medicine refills of three months or more. In this pre-post longitudinal study, we determined hypertension and HIV treatment …

View Details Source
Online interprofessional education for in-service health-care providers improved HIV performance indicators at health facilities in Uganda: a targeted training approach
Semitala F.C., Sewankambo N.K., Kimera I.D., Muddu M., Wanyina S., Bwayo D., Namusoke-Magongo E.
2022
Journal, Article
Health Research

Background: The Makerere University Education for Interprofessional HIV Service Delivery in Uganda capacity-building programme provides online, in-service interprofessional education to HIV health-care providers through a case-based approach. We used this …

View Details Source
A food-based approach could improve dietary adequacy for 12â23-month-old Eastern Ugandan children
Kimere N C, Nambooze J, Lim H, Bulungu A L.S, Wellard K, Ferguson E L
2022
Journal, Article
Health Research

Little is known about dietary adequacy, for young Ugandan children, or context-specific food choices to improve it. This study estimated the percentage of breastfed 12â23-month-old rural Eastern Ugandan children (nâ=â114) …

View Details Source
Characterising antibody avidity in individuals of varied Mycobacterium tuberculosis infection status using surface plasmon resonance
Bagaya Bernard S., Kimuda Simon G., Biraro Irene Andia, Raynes John G., Cose Stephen
2018
Journal, Article
Health Research

MEDLINE Abstract: There is increasing evidence supporting a role for antibodies in protection against tuberculosis (TB), with functional antibodies being described in the latent state of TB infection. Antibody avidity …

View Details Source
Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays
KimudaMagambo Phillip, Laming Dustin, Hoppe Heinrich C., Tastan Bishop Ãzlem
2019
Journal, Article
Health Research

MEDLINE Abstract: Pteridine reductase 1 (PTR1) is a trypanosomatid multifunctional enzyme that provides a mechanism for escape of dihydrofolate reductase (DHFR) inhibition. This is because PTR1 can reduce pterins and …

View Details Source
Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection
Cose Stephen, KimudaSimon G., Nalwoga Angela, Levin Jonathan, Franken Kees L. M. C., Ottenhoff Tom H. M., Elliott Alison M., Andia-Biraro Irene
2017
Journal, Article
Health Research

MEDLINE Abstract: Latent tuberculosis infection (LTBI) is evidence of immunological control of tuberculosis. Dormancy survival regulator (DosR) regulon-encoded proteins may have a role in the maintenance of LTBI. T cell …

View Details Source
Protective effects of pioglitazone and/or liraglutide on pancreatic beta-cells in db/db mice: Comparison of their effects between in an early and advanced stage of diabetes
Kimura T, Kaneto H, Shimoda M, Hirukawa H, Okauchi S, Kohara K, Hamamoto S, Tawaramoto K, Hashiramoto M, Kaku K
2015
Journal, Article
Health Research

The aim was to compare the protective effects of pioglitazone (PIO) and/or liraglutide (LIRA) on beta-cells with the progression of diabetes. Male db/db mice were treated with PIO and/or LIRA …

View Details
Safety and Effectiveness of Sodium Stibogluconate and Paromomycin Combination for the Treatment of Visceral Leishmaniasis in Eastern Africa: Results from a Pharmacovigilance Programme
Hailu A, Kimutai R, Musa AM, Njoroge S, Omollo R, Alves F, Khalil EAG, Diro E, Soipei P, Musa B and others...
2017
Journal, Article
Health Research

Introduction In 2010, WHO recommended a new first-line treatment for visceral leishmaniasis (VL) in Eastern Africa. The new treatment, a combination of intravenous (IV) or intramuscular (IM) sodium stibogluconate (SSG) …

View Details
Incidence and risk predictors of acute kidney injury among HIV-positive patients presenting with sepsis in a low resource setting
Nuwagira E, Kimweri D, Muhindo R, Ategeka J, Muyindike W, Ceasor F
2021
Journal, Article
Health Research

Background Acute kidney injury (AKI) is a frequently encountered clinical condition in critically ill patients and is associated with increased morbidity and mortality. In our resource-limited setting (RLS), the most …

View Details
AI Research Assistant
AI-powered research assistance. Uses the Digital Evidence Base as the Knowledge source.