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What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

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What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

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What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

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What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

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What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

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What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

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References (4020)

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A livelihood intervention to improve economic and psychosocial well-being in rural Uganda: Longitudinal pilot study
Tsai A.C., Bangsberg D.R., Atuhumuza E., Kakuhikire B., Suquillo D., Mushavi R., Perkins J.M., Venkataramani A.S., Weiser S.D.
2016
Journal, Article
Health Research
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The Effects of ACT Treatment and TS Prophylaxis on Plasmodium falciparum Gametocytemia in a Cohort of Young Ugandan Children
Kakuru A, Wanzira H, Kamya MR, Tappero JW, Arinaitwe E, Dorsey G, Homsy J, Bigira V, Muhindo M, Jagannathan P and others...
2013
Journal, Article
Health Research

Artemisinin-based combination therapies (ACTs) and trimethoprim-sulfamethoxazole (TS) prophylaxis are important tools for malaria control, but there are concerns about their effect on gametocytes, the stage of the parasite responsible for …

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Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected ugandan children
Achan J, Kakuru A, Ikilezi G, Mwangwa F, Charlebois E, Havlir D, Ruel T, Arinaitwe E, Dorsey G, Kamya M R and others...
2014
Journal, Article
Health Research

Background.âArtemisinin-based combination therapies (ACTs) are highly efficacious and safe, but data from human immunodeficiency virus (HIV)âinfected children concurrently receiving antiretroviral therapy (ART) and ACTs are limited.Methods.âWe evaluated 28-day outcomes following …

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Dihydroartemisinin-Piperaquine for the Prevention of Malaria in Pregnancy
Kakuru A, Natureeba P, Clark TD, Kamya MR, Havlir DV, Dorsey G, Olwoch P, Charlebois ED, Ategeka J, Jagannathan P and others...
2016
Journal, Article
Health Research

BACKGROUNDIntermittent treatment with sulfadoxine-pyrimethamine is widely recommended for the prevention of malaria in pregnant women in Africa. However, with the spread of resistance to sulfadoxine-pyrimethamine, new interventions are needed.METHODSWe conducted …

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Malaria burden in a birth cohort of HIV-exposed uninfected Ugandan infants living in a high malaria transmission setting
Kakuru A, Ruel T, Natureeba P, Cohan D, Dorsey G, Kamya M R, Clark T D, Muhindo M K, Havlir D V
2016
Journal, Article
Health Research

AbstractBackground: HIV-exposed, uninfected (HEU) infants suffer high morbidity and mortality in the first year of life compared to HIV-unexposed, uninfected (HUU) infants, but accurate data on the contribution of malaria …

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ASSOCIATION BETWEEN INDOOR RESIDUAL SPRAYING OF INSECTICIDE AND IMPROVED BIRTH OUTCOMES AMONG HIV-INFECTED PREGNANT WOMEN IN UGANDA
et al, Kakuru A., Koss C., Natureeba P., Roh M., Shiboski S., Global Health Group Malaria Elimination Initiative U. S. A.
2017
Journal, Article
Health Research

WATERLIT Abstract: Despite effective interventions to prevent malaria during pregnancy, the risk of adverse birth outcomes among HIV-infected pregnant women living in sub-Saharan Africa remains high. A recent study demonstrated …

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Impact of Plasmodium falciparum malaria and intermittent preventive treatment of malaria in pregnancy on the risk of malaria in infants: a systematic review
Dorsey G., Kakuru A., Staedke S. G., Rogerson S., Chandramohan D.
2019
Journal, Article
Health Research

BACKGROUND: Studies of the association between malaria in pregnancy (MiP) and malaria during infancy have provided mixed results. A systematic review was conducted to evaluate available evidence on the impact …

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Impact of intermittent preventive treatment of malaria in pregnancy with dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine on the incidence of malaria in infancy: A randomized controlled trial
Dorsey G., Kajubi R., Jagannathan P., Ochieng T., Kakuru A., Kamya M.R., Clark T.D., Havlir D.V., Chandramohan D., Ochokoru H. and others...
2020
Journal, Article
Health Research

Background: Intermittent preventive treatment of malaria during pregnancy (IPTp) with dihydroartemisinin-piperaquine (DP) significantly reduces the burden of malaria during pregnancy compared to sulfadoxine-pyrimethamine (SP), the current standard of care, but …

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Infant sex modifies associations between placental malaria and risk of malaria in infancy
Dorsey G., Kajubi R., Jagannathan P., Ochieng T., Kakuru A., Kamya M.R., Clark T.D., Havlir D.V., Chandramohan D., Ochokoru H. and others...
2020
Journal, Article
Health Research

Background: Placental malaria (PM) has been associated with a higher risk of malaria during infancy. However, it is unclear whether this association is causal, and is modified by infant sex, …

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Central Nervous System Tumors in Uganda: Outcomes of Surgical Treatment and Complications Assessed Through Telephone Survey
Haglund MM, Kiryabwire J, Muhumuza M, Ssenyonjo H, Mukasa J, Vaca SD, Nalwanga J, Grant GA, Kakusa BW, Xu LW
2019
Journal, Article
Health Research

BACKGROUND: Uganda has one of the largest unmet neurosurgical needs in the world, but has seen major improvements in neurosurgery-largely centered at Mulago National Referral Hospital (MNRH). This study implements …

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