Digital Evidence Base Logo
Filters
SDGs
Priority Areas
Research Outcomes
Document Type
Year
What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

View Details
What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

View Details
What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

View Details
What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

View Details
What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

View Details
What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

View Details
What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

View Details
What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

View Details
Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

View Details
What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

View Details

References (4020)

Show:
Health services strengthening in Africa - research is a key component S. Jaffar et al
Corrah Tumani, Mboup Souleymane, Jaffar Shabbar, Lazarus Jeffrey V., Onyebujoh Philip, Chakaya Jeremiah, Garrib Anupam, Mwaba Peter, Bellis Kevin, Egwaga Saidi and others...
2010
Journal, Article
Health Research

The author reflects on the importance of strengthening the health services in Africa. He states that performing research is the most important part of the strengthening process. The major challenge …

View Details Source
Controlling diabetes and hypertension in sub-Saharan Africa: lessons from HIV programmes
Lazarus J.V., Mutungi G., Jaffar S., Ramaiya K., Karekezi C., Sewankambo N., Ruhweza Katahoire A., Kraef C., Musinguzi J., Birungi J. and others...
2021
Journal, Article
Health Research
View Details Source
Childhood Tuberculosis and Malnutrition
Mupere Ezekiel, Jaganath Devan
2012
Journal, Article
Health Research

Despite the burden of both malnutrition and tuberculosis in children worldwide, there are few studies on the mechanisms that underlie this relationship. From available research, it appears that malnutrition is …

View Details Source
A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda
Cattamanchi A, Andama A, Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M and others...
2021
Journal, Article
Health Research

Background. Xpert MTB/RIF Ultra (Xpert Ultra) has improved the sensitivity to detect pulmonary tuberculosis (TB) in adults. However, there have been limited prospective evaluations of its diagnostic accuracy in children.Methods. …

View Details
Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda
Kakuru A, Kamya MR, Rosenthal PJ, Arinaitwe E, Greenhouse B, Dorsey G, Kaharuza F, Tappero J, Jagannathan P, Muhindo MK
2012
Journal, Article
Health Research

Background: The burden of malaria has decreased in parts of Africa following the scaling up of control interventions. However, similar data are limited from high transmission settings.Methods: A cohort of …

View Details
IFNI|/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children
Kamya Moses R., Jagannathan Prasanna, Dorsey Grant, Eccles-James Ijeoma, Bowen Katherine, Nankya Felistas, Auma Ann, Wamala Samuel, Ebusu Charles, Muhindo Mary K. and others...
2014
Journal, Article
Health Research

MEDLINE Abstract: Although evidence suggests that T cells are critical for immunity to malaria, reliable T cell correlates of exposure to and protection from malaria among children living in endemic …

View Details Source
Loss and dysfunction of V delta 2(+) gamma delta T cells are associated with clinical tolerance to malaria
Kamya MR, Tappero JW, Arinaitwe E, Greenhouse B, Dorsey G, Jagannathan P, Muhindo MK, Kim CC, Nankya F, Bowen K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The V delta 2(+) subset of gamma delta T cells …

View Details
Loss and dysfunction of Vδ2+γδ T cells are associated with clinical tolerance to malaria
Arinaitwe E, Greenhouse B, Dorsey G, Kamya M R, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Kim C C, Muhindo M K and others...
2014
Journal, Article
Health Research

Although clinical immunity to malaria eventually develops among children living in endemic settings, the underlying immunologic mechanisms are not known. The Vδ2+ subset of γδ T cells have intrinsic reactivity …

View Details Source
IFN gamma Responses to Pre-erythrocytic and Blood-stage Malaria Antigens Exhibit Differential Associations With Past Exposure and Subsequent Protection
Kamya MR, Dorsey G, Bigira V, Jagannathan P, Nankya F, Bowen K, Eccles-James I, Feeney ME, Stoyanov C, Sikyomu E and others...
2015
Journal, Article
Health Research

Background. The malaria-specific T-cell response is believed to be important for protective immunity. Antimalarial chemoprevention may affect this response by altering exposure to malaria antigens.Methods.aEuro integral We performed interferon gamma …

View Details
AI Research Assistant
AI-powered research assistance. Uses the Digital Evidence Base as the Knowledge source.