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What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

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What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

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What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

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What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

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What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

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What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

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References (4020)

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A qualitative investigation of the psychosocial services utilised by care-givers of patients with Alzheimer's disease and related dementias in southwestern Uganda
Abaasa C, Obua C, Wakida EK, Rukundo GZ
Journal, Article
Health Research

Individuals with Alzheimer's disease and related dementias often require substantial support from other people. Much of the care-giving is from family members who eventually experience physical, emotional and financial stress, …

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Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial
A5263 AMC066 Protocol Team, Krown SE, Moser CB, MacPhail P, Matining RM, Godfrey C, Caruso SR, Hosseinipour MC, Samaneka W, Nyirenda M and others...
2020
Journal, Article
Health Research

Background Optimal treatment regimens for AIDS-associated Kaposi sarcoma, a frequent contributor to morbidity and mortality among people with HIV, have not been systematically evaluated in low-income and middle-income countries, where …

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Prevalence, knowledge and practices of shisha smoking among youth in Kampala City, Uganda
Aanyu C, Kadobera D, Apolot RR, Kisakye AN, Nsubuga P, Bazeyo W, Ddamulira JB
2019
Journal, Article
Health Research

Introduction: globally tobacco use kills more than seven million people annually, a figure expected to rise to 8 million deaths every year by 2030. Though perceived as safe, shisha smoking …

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Comparison of HIV incidence estimated in clinical trial and observational cohort settings in a high risk fishing population in Uganda: Implications for sample size estimates
Abaasa A, Asiki G, Kamali A, Price MA, Ruzagira E, Kibengo F, Bahemuka U, Fast PE
2016
Journal, Article
Health Research

Background: Clinical trial participants may differ from the source population due to the demands of trial participation and self-selection, inadvertent selection of a lower-risk group, or both. We investigated the …

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Uptake of hormonal contraceptives and correlates of uptake in a phase III clinical trial in rural South Western Uganda
Abaasa A, Levin J, Kamali A, Gafos M, Anywaine Z, Nunn A, Crook A, McCormack S
2017
Journal, Article
Health Research

Background: Use of a reliable contraception method has become an inclusion criterion in prevention trials to minimize time off product. We report on hormonal contraceptive prevalence, uptake, sustained use and …

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Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and Schistosoma mansoni co-infected patients: a randomised controlled trial
Abaasa A., Kamali A., Asiki G., Obuku Ekii A., Wanyenze J., Pala P., G J. van Dam, Corstjens Plam, Hughes P., Ding S. and others...
2018
Journal, Article
Health Research

Background: It has been hypothesised that Schistosoma co-infection exacerbates HIV progression, and hence anthelminthic intervention in co-infected individuals will delay it. We evaluated effects of high-intensity versus low-intensity praziquantel treatment …

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Utility of Different Adherence Measures for PrEP: Patterns and Incremental Value
Abaasa A, Kamali A, Kibengo F, Hendrix C, Gandhi M, Anderson P, Sanders EJ, Mutua G, Bumpus NN, Priddy F and others...
2018
Journal, Article
Health Research

Measuring PrEP adherence remains challenging. In 2009-2010, the International AIDS Vaccine Initiative randomized phase II trial participants to daily tenofovir disoproxil fumarate/emtricitabine or placebo in Uganda and Kenya. Adherence was …

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Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and Schistosoma mansoni co-infected patients: A randomised controlled trial
Abaasa A, Asiki G, Kaleebu P, Kamali A, Wanyenze J, Pala P, van Dam G J, Hughes P, Ding S, Pantaleo G and others...
2019
Journal, Article
Health Research

Background: Schistosomaexacerbates HIV progression, and hence anthelminthic intervention inco-infected individuals will delay it. We evaluated effects of high-intensityversus low-intensity praziquantel treatment of schistosomiasis on HIV diseaseprogression among co-infected patients from …

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Simulated vaccine efficacy trials to estimate HIV incidence for actual vaccine clinical trials in key populations in Uganda
Abaasa A, Kaleebu P, Kamali A, Fast PE, Nash S, Mayanja Y, Price M, Todd J
2019
Journal, Article
Health Research

Background: Fisherfolks (FF) and female sex workers (FSW) in Uganda could be suitable key populations for HIV vaccine efficacy trials because of the high HIV incidence and good retention in …

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Comparison of HIV Risk Behaviors Between Clinical Trials and Observational Cohorts in Uganda
Abaasa A, Kaleebu P, Price MA, Fast PE, Nash S, Mayanja Y, Todd J
2020
Journal, Article
Health Research

Many key populations have high-risk behaviors for HIV infection making them suitable for HIV vaccine efficacy trials. However, these behaviors may change when participants enroll into a trial. We used …

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