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What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

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What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

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What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

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What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

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What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

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What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

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References (4020)

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Severe neurological sequelae and behaviour problems after cerebral malaria in Ugandan children
Idro R., Kakooza-Mwesige A., Balyejjussa S., Mirembe G., Mugasha C., Tugumisirize J., Byarugaba J.
2010
Journal, Article
Health Research
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Nodding syndrome in Ugandan children-clinical features, brain imaging and complications: A case series
Nankunda J, Bangirana P, Nalugya J, Opoka R O, Namusoke H, Idro R, Tumwine J K, Kiguli S, Aanyu H T, Kakooza-Mwesige A and others...
2013
Journal, Article
Health Research

Objectives Nodding syndrome is a devastating neurological disorder of uncertain aetiology affecting children in Africa. There is no diagnostic test, and risk factors and symptoms that would allow early diagnosis …

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Proposed guidelines for the management of nodding syndrome
Abbo C., Idro R., Makumbi I., Musubire K.A., Byamah Mutamba B., Namusoke H., Muron J., Oriyabuzu R., Ssekyewa J., Okot C. and others...
2013
Journal, Article
Health Research
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Patients with nodding syndrome in Uganda improve with symptomatic treatment: A cross-sectional study
Musubire A K, Abbo C, Opoka R O, Namusoke H, Idro R, Kakooza-Mwesige A, Mwaka A D, Mutamba B B, Opar B T
2014
Journal, Article
Health Research

Objectives: Nodding syndrome (NS) is a poorlyunderstood neurological disorder affecting thousandsof children in Africa. In March 2012, we introduced atreatment intervention that aimed to providesymptomatic relief. This intervention included sodiumvalproate …

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Cerebral malaria is associated with long-term mental health disorders: A cross sectional survey of a long-term cohort
Bangirana P, Nalugya J, John C C, Opoka R O, Idro R, Kakooza-Mwesige A, Asea B, Ssebyala K, Lubowa S K, Semrud-Clikeman M
2016
Journal, Article
Health Research

Background: Cerebral malaria (CM) and severe malarial anaemia (SMA) are associated with neuroâdevelopmentalimpairment in African children, but longâterm mental health disorders in these children are not well defined.Methods: A cohort …

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The natural history of nodding syndrome
Idro Richard, Ogwang Rodney, Kayongo Edward, Gumisiriza Norbert, Lanyero Agnes, Kakooza-Mwesige Angelina, Opar Bernard
2018
Journal, Article
Health Research

MEDLINE Abstract: Nodding syndrome is a poorly understood acquired disorder affecting children in sub-Saharan Africa. The aetiology and pathogenesis are unknown, and no specific treatment is available. Affected children have …

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Doxycycline for the treatment of nodding syndrome (DONS); the study protocol of a phase II randomised controlled trial
Abbo C, Anguzu R, Idro R, Opar B, Elliott A, Nakamya P, Ogwang R, Akun P, Mwaka AD, Taylor M and others...
2019
Journal, Article
Health Research

BackgroundNodding syndrome is a poorly understood neurological disorder of unknown aetiology, affecting several thousand children in Africa. There has been a consistent epidemiological association with infection by the filarial parasite, …

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Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome
John Chandy C., IdroRichard, Marsh Kevin, Newton Charles R. J.
2010
Journal, Article
Health Research

MEDLINE Abstract: Cerebral malaria is the most severe neurological complication of infection with Plasmodium falciparum. With >575,000 cases annually, children in sub-Saharan Africa are the most affected. Surviving patients have …

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Trends in hepatitis B virus testing practices and management in HIV clinics across sub-Saharan Africa
Ocama P, IeDEA Collaboration, Coffie PA, Egger M, Vinikoor MJ, Zannou M, Diero L, Patassi A, Kuniholm MH, Seydi M and others...
2017
Journal, Article
Health Research

Background: Approximately 8% of HIV-infected individuals are co-infected with hepatitis B virus (HBV) in sub-Saharan Africa (SSA). Knowledge of HBV status is important to guide optimal selection of antiretroviral therapy …

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Impact of Universal Antiretroviral Treatment Eligibility on Rapid Treatment Initiation Among Young Adolescents with Human Immunodeficiency Virus in Sub-Saharan Africa
Nakigozi G, Phiri S, IeDEA Consortium, Tymejczyk O, Brazier E, Wools-Kaloustian K, Davies MA, Dilorenzo M, Edmonds A, Vreeman R and others...
2020
Journal, Article
Health Research

Background. Young adolescents with perinatally acquired human immunodeficiency virus (HIV) are at risk for poor care outcomes. We examined whether universal antiretroviral treatment (ART) eligibility policies (Treat All) improved rapid …

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