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What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

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What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

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What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

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What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

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What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

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What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

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References (4020)

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P-A12âAssessing quality of HIV treatment in the United States Military HIV Research Program/President's Emergency Plan for AIDS Relief (PEPFAR)-supported programs in Africa
Hughes Lindsay, Hamm Tiffany, Crawford Keith, Lenneman Tessa, Kibuuka Hannah, Maswai Jonah, Clinkscales Jessica, Robb Merlin, Michael Nelson
2014
Journal, Article
Health Research

Following rapid scale up of ART, attention is now focused on improving quality of care and identifying populations and interventions to maximize impact and long-term effectiveness. Viral load, considered the …

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Impact of Exposure to Long Lasting Insecticide Treated Nets on Mosquito Survival and Behaviour at the Net Interface in Insecticide Susceptible and Resistant Strains of the Afrotropical Anopheles Mosquito
Hughes Angela Jane
2018
Dissertation
Health Research

The central role of long-lasting insecticidal nets (LLINs) in malaria prevention in Africa is threatened by insecticide resistance. Little is known about mosquito behaviour near, or of the importance of …

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Efavirenz-Based Antiretroviral Therapy Reduces Artemether-Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women
Hughes E, Mwebaza N, Huang LS, Kajubi R, Nguyen V, Nyunt MM, Orukan F, Mwima MW, Parikh S, Aweeka F
2020
Journal, Article
Health Research

Background: The choice of malaria treatment for HIV-infected pregnant women receiving efavirenz-based antiretroviral therapy must consider the potential impact of drug interactions on antimalarial exposure and clinical response. The aim …

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Piperaquine Exposure Is Altered by Pregnancy, HIV, and Nutritional Status in Ugandan Women
Zhang N, Kakuru A, Havlir D, Kamya M, Natureeba P, Dorsey G, Rosenthal P J, Huang L, Muhindo M, Hughes E and others...
2020
Journal, Article
Health Research

Dihydroartemisinin-piperaquine (DHA-PQ) provides highly effective therapy and chemoprevention for malaria in pregnant African women. PQ concentrations of >10.3âng/ml have been associated with reduced maternal parasitemia, placental malaria, and improved birth …

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Neurosurgical Decision-Making and Ethical Considerations in the Treatment of Traumatic Brain Injury
Hughes Jasmine
2022
Dissertation
Health Research

Globally, disparities in the availability of surgical care are prevalent, and for specialty care such as neurosurgery, services are typically scarce to non-existent. In low-and-middle-income countries, most medical centers have …

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Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women
Dorsey G., Rosenthal P.J., Hughes E., Wallender E., Kajubi R., Jagannathan P., Ochieng T., Kakuru A., Kamya M.R., Clark T.D. and others...
2022
Journal, Article
Health Research

BACKGROUND: Intermittent preventive treatment with monthly dihydroartemisinin-piperaquine (DHA-PQ) is highly effective at preventing both malaria during pregnancy and placental malaria. Piperaquine prolongs the corrected QT interval (QTc), and it is …

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Long-Term virological outcomes, failure and acquired resistance in a large cohort of Ugandan children
Kityo C, Mugyenyi P, Huibers M H.W, Boerma R S, Kaudha E, Sigaloff K C.E, Balinda S N, Bertagnolio S, Nakanjako R, Calis J C.J and others...
2019
Journal, Article
Health Research

Objectives: To evaluate long-term virological failure (VF) and drug resistance among HIV-infected Ugandan chil-dren on first-line ART.Methods: In a multicentre prospective cohort study, viral load (VL) and drug resistance mutations …

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PRECISION PUBLIC HEALTH AND PANDEMIC PREPAREDNESS: QUANTIFYING TRAVEL TIME TO HEALTH CARE AND LOCATIONS AT RISK FOR PATHOGEN TRANSMISSION
et al, Hulland E., Wiens K., Shirude S., Bell B., Rabinowitz P., Institute for Health Metrics, Evaluation Seattle W. A. United States
2019
Journal, Article
Health Research

AFRICAN DEVELOPMENT Abstract: Infectious disease threats exist even in places without evidence of past events, and without clear preparedness plans to prevent, detect, and respond to such threats, outbreaks can …

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Mechanisms of paediatric trauma at a rural hospital in Uganda.
Hulme P.
2010
Journal, Article
Health Research
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Mechanisms of trauma at a rural hospital in Uganda
Hulme P.
2010
Journal, Article
Health Research
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