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What health system strategies have low and middle income countries used to improve their maternal outcomes; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Maternal morbidity and mortality worldwide is a major public health problem with unacceptable effects on families and nations. The maternal mortality ratio for sub-Saharan Africa is estimated at almost …

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What is involved in an efficient relationship between the Ministry of Health and teaching hospitals in order for both institutions to effectively meet their objectives; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Teaching hospitals play a critical role in health care, medical education, and research. They are important to the Ministry of Health, which is responsible for providing quality healthcare to …

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What is the cost of diagnosing a new sputum smear positive TB case in children in low income settings; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Diagnosing tuberculosis (TB) in children, particularly sputum smear-positive TB, presents challenges in low-income countries. The process involves a series of steps, including clinical examinations, tuberculin skin testing, and bacteriological …

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What is the effect of counseling in unwanted pregnancy; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Unintended pregnancies affect a significant proportion of women worldwide, with a substantial number leading to induced abortions. In Uganda, a high prevalence of unintended pregnancies and a growing desire …

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What is the evidence for the effectiveness, safety and acceptability of âReady-To-Use Feedsâ; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Malnutrition rates in Uganda are high, with a significant proportion of children under 5 suffering from chronic and acute malnutrition. Ready-to-Use Therapeutic Foods (RUTF), known as RUTAFA in Uganda, …

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What is the role of stem cell therapy in the management of noncommunicable diseases? How does it work and what are its implications on the health system; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: The World Health Organization (WHO) has reported a global shift from infectious to non-communicable diseases (NCDs), which are now the leading causes of death worldwide. Cell-based therapy, or regenerative …

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What role can the regional tier play in facilitating health services delivery; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: Many countries are adopting reforms such as decentralization to improve public systems and service delivery by transferring authority and resources closer to the end-users. The regional tier approach, involving …

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What would be the appropriate Health Financing Strategy for Uganda; A Rapid Response Brief
ACRES
2011
brief
Health Research

Background: In Uganda, nearly 5% of households face catastrophic health expenditures, and 2.3% are impoverished due to medical bills. This situation prompted the World Health Organization (WHO) to urge member …

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Management of (expensive) medical equipment; lessons from other countries; A Rapid Response Brief
ACRES
2012
brief
Health Research

Background: Effective health technology management (HTM) is essential for delivering safe, equitable, and quality health care. However, the rising costs of healthcare, driven in part by advancing medical technology, pose …

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What are the arrangement options for the accreditation of health service providers in low and middle-income countries (LMICs); A Rapid Response Brief
ACRES
2012
brief
Health Research

Background:National accreditation systems aim to provide accreditation services to healthcare facilities. Accreditation can be used at the national level for external assessment of health services and as a tool for …

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References (4020)

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Feasibility of community at-home dried blood spot collection combined with pooled reverse transcription PCR as a viable and convenient method for malaria epidemiology studies
Balkus JE, Hergott DEB, Owalla TJ, Apio B, Lema J, Cemeri B, Akileng A, Seilie AM, Chavtur C, Staubus W and others...
2022
Journal, Article
Health Research

Background Many Plasmodium infections in endemic regions exist at densities below the limit of detection of standard diagnostic tools. These infections threaten control efforts and may impact vaccine and therapeutic …

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Earlier initiation of antiretroviral therapy, increased tuberculosis case finding and reduced mortality in a setting of improved HIV care: a retrospective cohort study
Kambugu A, Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA
2012
Journal, Article
Health Research

Objectives High early mortality after antiretroviral therapy (ART) initiation in resource-limited settings is associated with low baseline CD4 cell counts and a high burden of opportunistic infections. Our large urban …

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Integration of HIV and TB Services Results in Improved TB Treatment Outcomes and Earlier Prioritized ART Initiation in a Large Urban HIV Clinic in Uganda
Castelnuovo B, Manabe YC, Hermans SM, Hoepelman AIM, Lange JMA, Katabira C, Mbidde P, Coutinho A
2012
Journal, Article
Health Research

Background: The World Health Organization recommends that treatment of tuberculosis (TB) in HIV-infected patients should be integrated with HIV care. In December 2008, a separate outdoor-integrated TB/HIV clinic was instituted …

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Unrecognised tuberculosis at antiretroviral therapy initiation is associated with lower CD4+T cell recovery
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2012
Journal, Article
Health Research

Objectives To investigate whether an unrecognised diagnosis of tuberculosis (TB) at the start of antiretroviral therapy (ART) influences subsequent CD4+ T cell (CD4) count recovery in an urban HIV clinic …

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Risk of tuberculosis after antiretroviral treatment initiation: a comparison between efavirenz and nevirapine using inverse probability weighting
Manabe YC, Hermans SM, van Leth F, Hoepelman AIM, Lange JMA, Kiragga AN
2013
Journal, Article
Health Research

Background: There is a high incidence of tuberculosis (TB) early after antiretroviral therapy (ART) initiation. This historical cohort study evaluated the association of efavirenz (EFV) compared to nevirapine (NVP) with …

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Treatment decisions and mortality in HIV-positive presumptive smear-negative TB in the Xpert (TM) MTB/RIF era: a cohort study
Colebunders R, Castelnuovo B, Parkes-Ratanshi R, Manabe YC, Hermans SM, Babirye JA, Mbabazi O, Kakooza F, Sekaggya-Wiltshire C
2017
Journal, Article
Health Research

Background: The Xpert (TM) MTB/RIF (XP) has a higher sensitivity than sputum smear microscopy (70% versus 35%) for TB diagnosis and has been endorsed by the WHO for TB high …

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Development and Characterization of Broadly Cross-reactive Monoclonal Antibodies Against All Known Ebolavirus Species
Hernandez H., Marceau C., Halliday H., Callison J., Borisevich V., Escaffre O., Creech J., Feldmann H., Rockx B.
2015
Journal, Article
Health Research
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Effective strategies used to describe and address the burden of sickle cell disease in the Republic of Uganda: The Uganda Sickle Surveillance Study
Hernandez Arielle G.
2019
Dissertation
Health Research

Background:Sickle cell disease (SCD) contributes substantially to childhood mortality in sub-Saharan Africa. In the Republic of Uganda, the number of annual SCD births and the geographical distribution of the disease …

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Operational analysis of the national sickle cell screening programme in the Republic of Uganda
Hernandez Arielle G, Kiyaga Charles, Howard Thad A, Ssewanyana Isaac, Ndeezi Grace, Aceng Jane R, Ware Russell E
2021
Journal, Article
Health Research

Background: Sickle cell anaemia is a common global life-threatening haematological disorder. Most affected births occur in sub-Saharan Africa where children usually go undiagnosed and die early in life. Uganda's national …

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